
ROS detection in a cell-based format using the Promega ROS-Glo™ assay
There are many ways to monitor ROS generation. But few are as simple, fast, and sensitive as performing Promega’s ROS-GloTM assay on BMG LABTECH’s microplate readers.
The PHERAstar® FSX is our most sensitive multi-mode reader for high-throughput screening, combining this sensitivity with fast read times. Thanks to the unique Optic Module system, Simultaneous Dual Emission, UV/vis spectrometer, AAS System, and dedicated AlphaScreen® and TRF lasers, the PHERAstar FSX will perform your assay with ease and speed, even in 3456-well microplates.
No longer worry about installing filters and dichroics: the PHERAstar FSX comes with easy-to-handle, assay-optimized Optic Modules which contain all application-specific filters, mirrors, dichroics and/or polarizers, and are automatically recognised by the plate reader. In addition, the PHERAstar FSX is equipped with four matched and assay-optimized photomultiplier tubes (PMTs) which are automatically selected for the relevant detection mode. You can also measure assays with two emission wavelengths at the same time thanks to the Simultaneous Dual Emission.
For HTS automation purposes, the PHERAstar FSX can be easily integrated into automated systems, and offers improved robotic integration capabilities and multi-user control.
There are many ways to monitor ROS generation. But few are as simple, fast, and sensitive as performing Promega’s ROS-GloTM assay on BMG LABTECH’s microplate readers.
Do you want to perform interaction studies without having to perform protein purification? Read here, how HiBiT CETSA can be used to study PROTAC-target interaction in an endogenous test system.
Difficulties comparing your results due to temperature variations? Read here how the cooling function of the PHERAstar FSX with AAS enables stable temperature and circumvents these problems.
Looking for a fast, easy, and sensitive way to monitor the glucose metabolism of your cell culture? Read here how the VANTAstar offers maximum ease of use in luminescence detection.
Looking for the possibility to discriminate between antioxidant and cytotoxic effects in living cell systems? Read here how the Light Up Cell System by Antioxidant Power opens up this approach.
Are you looking for new tools for Alzheimer's diagnosis? Read here how phospho-tau modifications can be detected with ELISAs and potentially used as biomarkers.
Karim, JA;Lambert, NA;Pioszak, AA; [2023]
Protein expression and purification 203 106215
Malebari, AM;E A Ahmed, H;Ihmaid, SK;Omar, AM;Muhammad, YA;Althagfan, SS;Aljuhani, N;A A El-Sayed, AA;Halawa, AH;El-Tahir, HM;Turkistani, SA;Almaghrabi, M;K B Aljohani, A;El-Agrody, AM;Abulkhair, HS; [2023]
Bioorganic chemistry 130 106255
Roy, CB;Goonetilleke, SN;Joseph, L;Krishnan, A;Saha, T;Kilian, A;Mather, DE; [2022]
Plants (Basel, Switzerland) 11(24)
Han, P;Wang, C;Zhang, W;Wu, Y;Wang, D;Zhao, S;Zhu, M; [2022]
Animal genetics
Hurst-Hess, KR;Phelps, GA;Wilt, LA;Lee, RE;Ghosh, P; [2022]
Tuberculosis (Edinburgh, Scotland) 138 102295
Körte, F;Wessendorf, CD;Schnabel, T;Herrmann, M;Schröppel, B;Stadelmann, K;Arefaine, E;Busch, L;Daum, R;Ahlswede, E;Hartmann, H; [2022]
RSC advances 12(53) 34381-34392
Intelligent microplate incubation
Microplate handling system
Low-volume measurements
Filters for a wide range of applications
Functional Microplate Reader Validation