Microbiological assays examine mechanisms in bacteria, viruses, and parasites. They are essential for understanding infectious diseases, their spread, treatment, and prevention.
Many assays assess the growth or reproduction of microbes. Bacteria, fungi and parasites are mainly quantified using the absorbance measurement mode, while the replication of viruses is typically measured by luminescence. All growth and replication assays need to be measured over time in order to determine growth rates. Time courses can be measured with all BMG LABTECH microplate readers. In addition, the instruments regulates the incubation temperature and atmosphere to desired O2 and CO2 values, generating optimal growth conditions.
BMG LABTECH's multi-mode plate readers can do much more than just growth measurements: they measure how a virus docks onto a cell, how viruses can be neutralized, what helps against biofilms, whether a substance has an antibiotic effect and much more. Learn more about virus detection methods and how to detect a virus with a microplate reader.
Search our resources section for information about specific applications, literature citations, videos, blog articles and many other publications. Many of the resources provided are associated with current and previous instrument models and versions.
Optimising your luminescence-based experiment and instrument settings can greatly benefit your assay results. BMG LABTECH microplate readers are the ideal measurement platform for this purpose.
Read how to detect endotoxins in only 15 minutes using the fluorescent PyroGene™ assay and a CLARIOstar Plus microplate reader with EDR function here.
Read here, how the growth of group B streptococcus can be monitored in real time by expression of a bright GFP mutant with the CLARIOstar® microplate reader.
Learn how absorbance-based assays report the activity of indispensable Schistosoma enzymes to study the effectiveness of new drugs and vaccines in live parasites and in real-time.
Rapid oxygen changes influence cellular respiration. The CLARIOstar® enables to successively measure mitochondrial oxidant generation after oxygen deprivation and re-oxygenation.
The validation of new promoters is often done by reporter gene constructs. Look at this application note which highlights the use of mCherry as a second reporter to optimise promoter validation.
OD600 is part of a lot of microbiology studies. Reason enough for us to use this article to explain why the method is used so intensively and what should be considered for the measurement.
Antibiotics, which are the last resort for many infections are threatened by upcoming resistances. Read here why microplate readers are an indispensable tool in combating antibiotic resistance.
Obligate anaerobic gut bacteria require an absolute anaerobic environment. Read how the FLUOstar Omega was used to develop new methods to study the human gut microbiome.
Want to incubate bacteria and monitor their growth in the same instrument? See how BMG LABTECH microplate readers support you in this.
Hoenes, K;Bauer, R;Spellerberg, B;Hessling, M; 
Antibiotics 10(3) 341
Sabir, S;Yu, T;Kuppusamy, R;Almohaywi, B;Iskander, G;Das, T;Willcox, M;Black, D;Kumar, N; 
Antibiotics 10(3) 321
Dinarvand, M;Spain, M; 
Antibiotics 10(3) 337
Pournejati, R;Gust, R;Sagasser, J;Kircher, B;Jöhrer, K;Ghanbari, MM;Karbalaei-Heidari, HR; 
Toxicology in vitro : an international journal published in association with BIBRA 73 105148
Yoshihara, K;Nagaoka, N;Umeno, A;Sonoda, A;Obika, H;Yoshida, Y;Van Meerbeek, B;Makita, Y; 
Materials 14(6) 1442
Zeng, P;Yi, L;Xu, J;Gao, W;Xu, C;Chen, S;Chan, KF;Wong, KY; 
Biochimica et biophysica acta. Biomembranes 1863(6) 183600
Read in this customer story how our microplate reader CLARIOstar Plus can help you with your Malaria Research.
The lab of Associate Professor Crystale Lim Siew Ying focusses on antibiotic resistance profiling.
David Bell and Miles Priestman from Imperial College London, talk about how to run a synthetic biology lab and how our microplate readers can help.
Kirsten Jensen from Imperial College London, talks about how to run a synthetic biology lab and how our microplate readers can help.
Christ Hirst, a Product Specialist at CyBio FeliX, talks about enabling automated synthetic biology research and how the CLARIOstar Plus can help.
Powerful and most sensitive HTS plate reader
Most flexible Plate Reader for Assay Development
Flexible microplate reader with simplified workflows
Upgradeable single and multi-mode microplate reader series
Microplate nephelometer for light-scattering and turbidity measurements
Absorbance plate reader with cuvette port