Microbiology is the study of bacteria, yeasts, parasites and more
Microbiological assays examine mechanisms in bacteria, viruses, and parasites. They are essential for understanding infectious diseases, their spread, treatment, and prevention. Here you can find out how well-suited BMG LABTECH plate readers are for all microbiological approaches.
Many assays assess the growth or reproduction of microbes. Bacteria, fungi and parasites are mainly quantified using the absorbance measurement mode, while the replication of viruses is typically measured by luminescence. All growth and replication assays, including those for bacterial growth, need to be measured over time in order to determine growth rates. Similarly, the effects of bacterial growth can also be determined over time, such as the increasing cytotoxicity induced by intracellular bacterial growth. Time courses can be measured with all BMG LABTECH microplate readers. In addition, the instruments regulates the incubation temperature and atmosphere to desired O2 and CO2 values, generating optimal growth conditions. Next to growth assays, microplate readers can also be used to quantify metabolic products of microorganisms like shown in the application note: Fluorescence analysis of reactive oxygen species (ROS) generated by six isolates of Aspergillus fumigatus.
BMG LABTECH's multi-mode plate readers can do much more than just growth measurements: they measure how a virus docks onto a cell, how viruses can be neutralized, how bacteria communicate with each other, what helps against biofilms, whether substances have antibiotic effects (including measurements to determine minimum inhibitory concentrations (or MICs), minimum bactericidal concentrations (or MBCs), novel antibiotics and much more. Learn more about virus detection methods and how to detect a virus with a microplate reader.
Mycology & yeasts
Bacteriology
Parasitology
Resources
Search our resources section for information about specific applications, literature citations, videos, blog articles and many other publications. Many of the resources provided are associated with current and previous instrument models and versions.
Screening for novel antibiotics in venom against Staphylococcus aureus
The threat of growing antibiotic resistance is constantly increasing. Find out here how venom fractions are emerging as a beacon of hope in the search for novel antibiotics.
The InToxSA assay, for quantifying Intracellular Cytotoxic S. aureus Phenotypes
Looking for a method to study intracellular bacterial cytotoxicity? This AppNote presents a novel method based on the monitoring of propidium iodide uptake with the CLARIOstar Plus.
Testing novel bacteriophages for antibacterial properties with a crystal violet biofilm quantification assay
Antibiotic resistance in bacteria is a growing threat to human health. Read this App note to learn how bacteriophage efficacy can be evaluated on microplate readers.
Establishing luminescence-based assays: miniaturised experiments help to optimise results
Optimising your luminescence-based experiment and instrument settings can greatly benefit your assay results. BMG LABTECH microplate readers are the ideal measurement platform for this purpose.
Faster PyroGene™ Detection of Endotoxin using Enhanced Dynamic Range on the CLARIOstar Plus
Read how to detect endotoxins in only 15 minutes using the fluorescent PyroGene™ assay and a CLARIOstar Plus microplate reader with EDR function here.
Expression of a stable green fluorescent protein mutant in group B streptococcus. Growth, detection and monitoring, with the CLARIOstar
Read here, how the growth of group B streptococcus can be monitored in real time by expression of a bright GFP mutant with the CLARIOstar® microplate reader.
Gene reporter assays
Gene reporter assays are sensitive and specific tools to study the regulation of gene expression. Learn about the different options available, their uses, and the benefits of running these types of assays on microplate readers.
The minimum bactericidal concentration of antibiotics
What is the minimum bactericidal concentration or MBC and what are its uses?
Minimum inhibitory concentration of antibiotics
What is the minimum inhibitory concentration or MIC and what are its uses?
Bacterial growth measurements on a microplate reader
Scientists measure bacterial growth in laboratories across the world but why is it so universal?
Quorum sensing: how bacteria stay in touch
Quorum sensing is a type of cell-to-cell communication in bacteria that depends on cell density. Find out how microplate readers can help advance quorum sensing research.
Advances in combating antimicrobial resistance
Antimicrobial resistance is a formidable problem across the world. Find out how microplate readers can help tackle resistant microbes.
Malaria research on the CLARIOstar Plus
Read in this customer story how our microplate reader CLARIOstar Plus can help you with your Malaria Research.
Quorum sensing inhibition: a possible answer to antibiotic resistance
The lab of Associate Professor Crystale Lim Siew Ying focusses on antibiotic resistance profiling.
A center for synthetic biology supports academics, start-ups and industry
David Bell and Miles Priestman from Imperial College London, talk about how to run a synthetic biology lab and how our microplate readers can help.
Running a synthetic biology lab with BMG LABTECH plate readers
Kirsten Jensen from Imperial College London, talks about how to run a synthetic biology lab and how our microplate readers can help.
Enabling automated synthetic biology research
Chris Hirst, a Product Specialist at CyBio FeliX, talks about enabling automated synthetic biology research and how the CLARIOstar Plus can help.
PHERAstar FSX
Powerful and most sensitive HTS plate reader
CLARIOstar Plus
Most flexible Plate Reader for Assay Development
VANTAstar
Flexible microplate reader with simplified workflows
Omega Series
Upgradeable single and multi-mode microplate reader series
NEPHELOstar Plus
Microplate nephelometer for light-scattering and turbidity measurements
SPECTROstar Nano
Absorbance plate reader with cuvette port