Immunology is the study of the immune system - what it is, how it functions, and how it is involved in health and disease. Explore how BMG LABTECH microplate readers can advance immunological research.
Immunology is the study of the immune system, which protects us from infection through many lines of defence and therefore is a vital branch of medical and biological sciences. If the immune system is not functioning properly it can lead to diseases such as autoimmunity, allergy, and cancer. The importance of immunological research is highlighted by past and present scientific breakthroughs including safe organ transplantations, the identification of blood groups, and the ubiquitous use of monoclonal antibodies throughout science and healthcare, immunology has changed the face of modern medicine.
Immunological research is continuing to expand our knowledge and understanding of how to treat significant health issues through ongoing efforts in in immunotherapy, autoimmune diseases, and vaccines for emerging pathogens. It also helps in areas like the development of quality control methods for substances like pyrogens which act through the immune system. Tests for pyrogens are needed to ensure the safety of pharmaceuticals, biologics and medical devices. The advances in microplate technology by BMG LABTECH have contributed towards immunological research including cancer immunotherapies and vaccine production using methods such as ELISA to quantify antibodies, antigens, proteins, and glycoproteins and cell-based assays to assess cellular signalling pathways, immune cell maturation or adhesion, as shown in the AppNotes: Bead-based Assay using pHrodo™ Red to Evaluate Phagosome Acidification or A leukocyte adhesion assay performed on a BMG LABTECH microplate reader. Explore the content below to understand how BMG LABTECH instruments can be further utilised in immunological research.
Search our resources section for information about specific applications, literature citations, videos, blog articles and many other publications. Many of the resources provided are associated with current and previous instrument models and versions.
Acidification is an important tool of innate immune cells. Read here how the pH sensor pHrodo Red and the CLARIOstar Plus with ACU help to track phagosome acidification in real-time.
Read in this AppNote, how cytokines can be measured and quantified with extraordinary sensitivity, using THUNDER™ Biomarker Assays in combination with the PHERAstar FSX.
Read here how optimised read conditions on the PHERAstar FSX elevate sensitivity and improve the suitability of miniaturised TRF immunoassays for high-throughput screening.
Track ubiquitination processes in real-time from mono- to polyubiquitination using TAMRA-labelled ubiquitin and the CLARIOstar’s excellent fluorescence polarization detection.
Tired of repeated wash steps for your ELISA assay? Check out the no-wash detection of SPARCL immunoassays on the CLARIOstar!
The ProteaseTag™ activity-dependent immunoassay provides a selective and quantitative measurement of active neutrophil elastase levels in patient sputum samples.
Pyrogen tests are vital to ensure the safety of different health interventions including pharmaceuticals, medical devices and an array of biological products. This blog looks at the different types of pyrogens as well as some of the widely used pyrogen tests.
Light scattering offers distinct advantages for scientists interested in immunology. Find out how the NEPHELOstar Plus is used for high-throughput immunological tests.
Vaccines are powerful tools to fight viral diseases. Read more about the science behind vaccines and what we can expect from vaccine development in the future.
Read here, how BMG LABTECH microplate readers can help at advancing cancer immunotherapy research.
Powerful and most sensitive HTS plate reader
Most flexible Plate Reader for Assay Development
Flexible microplate reader with simplified workflows
Upgradeable single and multi-mode microplate reader series
Absorbance plate reader with cuvette port
