LUMIstar Omega

Luminômetro de microplaca dedicado

O LUMIstar^® Omega é o poderoso leitor de microplacas de luminescência dedicado da BMG LABTECH, fornecendo leituras de ensaio de flash e brilho (Glow) altamente sensíveis. Este leitor de microplacas com certificação DLReady também pode ser equipado com emissão simultânea dupla para aplicações BRET e pode ser atualizado para um leitor do tipo multi-modo.

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Detection modes

Absorbance
Fluorescence intensity (incl. FRET)
Luminescence (incl. BRET)
Fluorescence polarization
AlphaScreen
Nephelometry
Time-resolved fluorescence
TR-FRET

Detalhes do produto Avaliações Notas de aplicação Publicações Especificações técnicas Acessórios Comparar leitor

LUMIstar Omega

O LUMIstar Omega é um leitor dedicado para medições de luminescência, incluindo BRET. Ele fornece leituras altamente sensíveis de todas as aplicações de luminescência em ensaios finais e cinéticos. Além disso, a detecção de emissões duplas simultâneas tornam possível a detecção de comprimento de onda múltiplo e as aplicações BRET.

Características

Ensaios tipo BRET, Flash e Brilho (Glow)
Medidas em placas de até 384 poços
Leitura por baixo e por cima dos poços
Incubação até 45 °C ou até 65 °C
Emissão Simultânea Dupla
Escaneamento de até 900 pontos na área útil dos poços
Injetores de alta precisão com injeção e detecção simultâneas

Tecnologias de leitor de microplacas

Gas Vent

BMG LABTECH offers two forms of gas control on its microplate readers. The Atmospheric Control Unit (ACU) for the CLARIOstar is a unique microprocessor-controlled unit that independently regulates both CO2 and O2 inside the microplate reader. Alternatively, the Gas Vent is a positive pressure gas purge through which the internal atmosphere of the microplate reader can be replaced.

Incubation and shaking

Shaking and incubation allow users to mix the well content and easily run measurements at elevated temperatures. The incubator controls the air temperature in the measurement chamber from room temperature up to 45°C, 60°C or 65°C. BMG LABTECH microplate readers are equipped with orbital, double-orbital or linear shaking with definable intensity, duration and direction of motion. These features are available on all BMG LABTECH plate readers.

Path length correction

Absorbance measurements such as DNA quantification or protein determination detected in a microplate reader are frequently compared and/or normalized to results from a 1 cm path length cuvette. All BMG LABTECH microplate readers have the ability to perform a 1 cm path length correction thanks to an internal fitting algorithm. Using this correction, data normalization to 1 cm path is given with only one mouse click.

Reagent injectors

Many of today's most popular assays such as enzyme kinetics, calcium flux, and dual luciferase require the ability to monitor a signal during and after the addition of a reagent. All BMG LABTECH readers, with the exception of the SPECTROstar Nano, can be equipped with up to two reagent injectors. Injectors enable reagent delivery to any plate format from 6 to 384 wells.

Simultaneous Dual Emission

Simultaneous Dual Emission (SDE) detection allows the measurement of two emitted wavelengths at the same time. It reduces plate read times and corrects for any signal variation due to differences in well volumes, concentrations, or fluctuations in excitation energy. SDE is the ideal tool for double-emission assays such as FRET, TR-FRET, fluorescence polarization and BRET, since the sample only has to be read once.

UV/vis spectrometer

BMG LABTECH was the first and is the only microplate reader manufacturer to equip its instruments with a UV/vis spectrometer for absorbance measurements. Similar to a monochromator, but much faster, the spectrometer will capture full-absorbance spectra from 220 to 1000 nm at a resolution of 1 nm in less than one second/well. Alternatively, up to eight discrete wavelengths can be collected at the same time.

Well-scanning

For non-homogeneous samples such as for cell-based assays, where the sample distribution is uneven across the well, a single reading in the centre of the well is inadequate. To overcome this problem, all BMG LABTECH readers come with an advanced Well Scanning feature that can take multiple measurements in each well with a resolution of up to 900 points/well. Alternatively, in spiral or orbital averaging mode, the reader takes several measurements for each well on a defined spiral or orbit and calculates an average.

Xenon Flash lamps

Microplate readers require a light source to provide the incident of light directed at the sample.

Cell-based assays assessing antioxidant capacity and cytotoxicity in living cells

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Comparing site specific phospho-tau in normal and Alzheimer's disease brains

Are you looking for new tools for Alzheimer's diagnosis? Read here how phospho-tau modifications can be detected with ELISAs and potentially used as biomarkers.

Differential activation of G proteins by synthetic cannabinoid receptor agonists, utilizing the CAMYEL BRET biosensor

Synthetic cannabinoids become increasingly associated to drug misuse. Read how the CAMYEL BRET biosensor can be used to study the associated signaling pathways in plate readers.

Testing novel bacteriophages for antibacterial properties with a crystal violet biofilm quantification assay

Antibiotic resistance in bacteria is a growing threat to human health. Read this App note to learn how bacteriophage efficacy can be evaluated on microplate readers.

Real-Time Cell Motility Tracking Increases the Throughput of Scratch Wound Assays

Interested in the real-time monitoring of wound healing without the use of a microscope? Read here how bioluminescent visualization of cells enables the analysis with microplate readers.

NextGenPCR™ evaluated with a fluorescence microplate reader accelerates testing for SARS-CoV-2 viral RNA

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Eco-physiological response and genotoxicity induced by crude petroleum oil in the potential phytoremediator Vinca rosea L

Hussein, ZS;Hegazy, AK;Mohamed, NH;El-Desouky, MA;Ibrahim, SD;Safwat, G; [2022]
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Savigni, DL;Chang, AY;Sorensen, NL;Papagianis, PC;Ahmadi-Noorbakhsh, S;Pillow, JJ;Noble, PB; [2022]
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Rezk, N;Abdelsattar, AS;Elzoghby, D;Agwa, MM;Abdelmoteleb, M;Aly, RG;Fayez, MS;Essam, K;Zaki, BM;El-Shibiny, A; [2022]
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Placental OLAH Levels Are Altered in Fetal Growth Restriction, Preeclampsia and Models of Placental Dysfunction

de Alwis, N;Beard, S;Binder, NK;Pritchard, N;Kaitu'u-Lino, TJ;Walker, SP;Stock, O;Groom, K;Petersen, S;Henry, A;Said, JM;Seeho, S;Kane, SC;Tong, S;Hui, L;Hannan, NJ; [2022]
Antioxidants (Basel, Switzerland) 11(9)

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