NEPHELOstar Plus

Name: NEPHELOstar Plus
Brand: BMG LABTECH
Rating: 4.7 (2 reviews)

Nefelômetro de microplacas para medições de dispersão de luz e turbidez

O primeiro e único nefelômetro de microplacas baseadas em laser do mundo foi desenvolvido para atender às demandas de alto rendimento para telas de solubilidade de compostos rápidos. O NEPHELOstar^® Plus detecta partículas insolúveis em amostras líquidas através da medição da luz dispersa para frente e pode ser usado para medições de turbidez, triagem de solubilidade de drogas, cinética de ligação de proteína, crescimento microbiano e controle de processo de petróleo.

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Modos de detecção

Absorbance
Fluorescence intensity (incl. FRET)
Luminescence (incl. BRET)
Fluorescence polarization
AlphaScreen
Nephelometry
Time-resolved fluorescence
TR-FRET

Detalhes do produto Avaliações Notas de aplicação Publicações Especificações técnicas Acessórios Comparar leitores

NEPHELOstar Plus

O NEPHELOstar Plus é um nefelômetro de microplacas com um diodo laser de alta intensidade. Pode ser até trinta vezes mais sensível do que os leitores de densidade óptica de transmissão tradicionais que medem a redução na luz direta que passa por um poço de amostra. Graças à sua velocidade, flexibilidade e desempenho, o NEPHELOstar Plus permite que mais aplicações sejam adaptadas à nefelometria laser baseada em microplacas do que nunca.

Características

Intensidade do laser ajustável e diâmetro do feixe
Medição em formato de microplaca de até 384 poços
Incubação de até 45 °C
Tremido linear, orbital e duplo orbital
Injetores de alta precisão com injeção e detecção simultânea de reagentes
Microplaca Stacker e robô compatível

Tecnologias de leitor de microplacas

Automation

Automation is a key feature in high-throughput screening. BMG LABTECH microplate readers have been successfully integrated into various robotic systems. Small footprint, multiple robotic software interfaces and an automation-friendly plate carrier guarantee an easy integration into all leading robotic platforms. All plate readers can be controlled through ActiveX or DDE interfaces. Moreover, the ASCII data output is the most versatile in the industry and works with most LIMS and automation platforms.

Gas Vent

BMG LABTECH offers two forms of gas control on its microplate readers. The Atmospheric Control Unit (ACU) for the CLARIOstar is a unique microprocessor-controlled unit that independently regulates both CO2 and O2 inside the microplate reader. Alternatively, the Gas Vent is a positive pressure gas purge through which the internal atmosphere of the microplate reader can be replaced.

Incubation and shaking

Shaking and incubation allow users to mix the well content and easily run measurements at elevated temperatures. The incubator controls the air temperature in the measurement chamber from room temperature up to 45°C, 60°C or 65°C. BMG LABTECH microplate readers are equipped with orbital, double-orbital or linear shaking with definable intensity, duration and direction of motion. These features are available on all BMG LABTECH plate readers.

Reagent injectors

Many of today's most popular assays such as enzyme kinetics, calcium flux, and dual luciferase require the ability to monitor a signal during and after the addition of a reagent. All BMG LABTECH readers, with the exception of the SPECTROstar Nano, can be equipped with up to two reagent injectors. Injectors enable reagent delivery to any plate format from 6 to 384 wells.

Improving throughput for assessing nephelometric turbidity units (NTUs) using the NEPHELOstar® Plus

Nephelometric turbidity units (NTUs) refer to the concentration of particles to describe the quality of water. Read how the NEPHELOstar® Plus microplate nephelometer determines NTUs in low sample volume.

Nephelometric monitoring growth of Candida albicans using BMG LABTECH's NEPHELOstar Plus

Laser nephelometry was used for the rapid determination of the solubility of potential antimycotic drug compounds and for the measurement of fungal growth in the microplate format.

Measuring of rheumatoid factors by the NEPHELOstar Plus microplate reader

An alternative method to test Rheumatoid Factors by microplate nephelometry provides an inexpensive assay that can be used in medium- to high-throughput labs. Read more here!

Monitoring of microbial growth curves by laser nephelometry

Laser nephelometry is a reliable and sensitive technique to monitor microbial growth. Check out its good correlation with absorbance turbidity measurements in this AppNote!

A fully automated kinetic solubility screen in 384-well plate format using nephelometry

Tired of performing solubility tests for your compound libraries? Nephelometry offers a rapid, reliable and low-cost method for kinetic solubility screenings in high-throughput!

Ver todas as notas de aplicação

Discovery of small molecule mechanistic target of rapamycin inhibitors as anti-aging and anti-cancer therapeutics

Chrienova, Z;Rysanek, D;Oleksak, P;Stary, D;Bajda, M;Reinis, M;Mikyskova, R;Novotny, O;Andrys, R;Skarka, A;Vasicova, P;Novak, J;Valis, M;Kuca, K;Hodny, Z;Nepovimova, E; [2022]
Frontiers in aging 61511166612 14 1048260

Read article

Exploring the Effect of Halogenation in a Series of Potent and Selective A2B Adenosine Receptor Antagonists

Prieto-Díaz, R;González-Gómez, M;Fojo-Carballo, H;Azuaje, J;El Maatougui, A;Majellaro, M;Loza, MI;Brea, J;Fernández-Dueñas, V;Paleo, MR;Díaz-Holguín, A;Garcia-Pinel, B;Mallo-Abreu, A;Estévez, JC;Andújar-Arias, A;García-Mera, X;Gomez-Tourino, I;Ciruela, F;Salas, CO;Gutiérrez-de-Terán, H;Sotelo, E; [2022]
Journal of medicinal chemistry

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Exploring ionic liquids based on pyrrolidinium and imidazolium cations with low toxicity towards Escherichia coli for designing sustainable bioprocesses

Hernández-Fernández, FJ;de Los Ríos, AP;Licence, P;Stephens, G; [2022]
Journal of 61511166610 360 192-197

Read article

Serum calcification propensity and its association with biochemical parameters and bone mineral density in hemodialysis patients

Kim, H;Kim, AJ;Ro, H;Chang, JH;Lee, HH;Chung, W;Jung, JY; [2022]
Kidney research and clinical practice

Read article

From Serendipity to Rational Identification of the 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one Core as a New Chemotype of AKT1 Inhibitors for Acute Myeloid Leukemia

Astolfi, A;Milano, F;Palazzotti, D;Brea, J;Pismataro, MC;Morlando, M;Tabarrini, O;Loza, MI;Massari, S;Martelli, MP;Barreca, ML; [2022]
Pharmaceutics 14(11)

Read article

Understanding opalescence measurements of biologics - a comparison study of methods, standards, and molecules

Kunz, P;Stuckenberger, E;Hausmann, K;Gentiluomo, L;Neustrup, M;Michalakis, S;Rieser, R;Romeijn, S;Wichmann, C;Windisch, R;Hawe, A;Jiskoot, W;Menzen, T; [2022]
International journal of pharmaceutics 628 122321

Read article

Ver todas as Publicações

Para mais efeitos: Acessórios para NEPHELOstar Plus

Compare two readers

SPECTROstar Nano

Absorbance plate reader with cuvette port

LUMIstar Omega

Dedicated microplate luminometer

SPECTROstar Omega

Absorbance plate reader with ultrafast UV/vis spectrometer

NEPHELOstar Plus

Microplate nephelometer for light-scattering and turbidity measurements

PHERAstar FSX

Powerful and most sensitive HTS plate reader

CLARIOstar Plus

Most flexible Plate Reader for Assay Development

FLUOstar Omega

Filter-based multi-mode microplate reader

VANTAstar

Flexible microplate reader with simplified workflows

NEPHELOstar Plus

Nefelômetro de microplacas para medições de dispersão de luz e turbidez

Modos de detecção

NEPHELOstar Plus

Características

Automation

Gas Vent

Incubation and shaking

Reagent injectors

Improving throughput for assessing nephelometric turbidity units (NTUs) using the NEPHELOstar® Plus

Nephelometric monitoring growth of Candida albicans using BMG LABTECH's NEPHELOstar Plus

Measuring of rheumatoid factors by the NEPHELOstar Plus microplate reader

Monitoring of microbial growth curves by laser nephelometry

A fully automated kinetic solubility screen in 384-well plate format using nephelometry

Discovery of small molecule mechanistic target of rapamycin inhibitors as anti-aging and anti-cancer therapeutics

Exploring the Effect of Halogenation in a Series of Potent and Selective A2B Adenosine Receptor Antagonists

Exploring ionic liquids based on pyrrolidinium and imidazolium cations with low toxicity towards Escherichia coli for designing sustainable bioprocesses

Serum calcification propensity and its association with biochemical parameters and bone mineral density in hemodialysis patients

From Serendipity to Rational Identification of the 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one Core as a New Chemotype of AKT1 Inhibitors for Acute Myeloid Leukemia

Understanding opalescence measurements of biologics - a comparison study of methods, standards, and molecules

Para mais efeitos: Acessórios para NEPHELOstar Plus

THERMOstar

Microplate Stacker

Atmospheric Control Unit

Compare dois leitores

Compare two readers

SPECTROstar Nano

LUMIstar Omega

SPECTROstar Omega

NEPHELOstar Plus

PHERAstar FSX

CLARIOstar Plus

FLUOstar Omega

VANTAstar