NEPHELOstar Plus

Microplate nephelometer for light-scattering and turbidity measurements

 

The world’s first and only laser-based microplate nephelometer was developed to meet high-throughput demands for fast compound solubility screens. The NEPHELOstar® Plus detects insoluble particles in liquid samples by measuring forward scattered light and can be used for turbidity measurements, drug solubility screening, protein binding kinetics, microbial growth, and petroleum process control.

Microplate reader NEPHELOstar Plus

Ratings

select-science 11-2

Great instrument invaluable to our work flows.

The Nephelostar is an important part of our workflow for SPR. All compounds are tested for...
4.7/5.0 (2)
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NEPHELOstar Plus

The NEPHELOstar Plus is a microplate nephelometer with a high-intensity laser diode. It can be up to thirty times more sensitive than traditional transmission optical density readers that measure the reduction in direct light passing through a sample well. Thanks to its speed, flexibility, and performance, the NEPHELOstar Plus allows more applications to be adapted to microplate-based laser nephelometry than ever before.

The NEPHELOstar Plus is for research use only.

Features

  • Adjustable laser intensity and beam diameter
  • Measurement in up to 384-well microplate format
  • Incubation up to 45°C
  • Linear, orbital and double-orbital shaking
  • High-precision injectors with simultaneous reagent injection and detection
  • Microplate Stacker and robot compatible
  • Easily integrated into automated systems
 

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Optional accessories

Our technologies

Automation

Automation is a key feature in high-throughput screening. BMG LABTECH microplate readers have been successfully integrated into various robotic systems. Small footprint, multiple robotic software interfaces and an automation-friendly plate carrier guarantee an easy integration into all leading robotic platforms. All plate readers can be controlled through ActiveX or DDE interfaces. Moreover, the ASCII data output is the most versatile in the industry and works with most LIMS and automation platforms.

Gas Vent

BMG LABTECH offers two forms of gas control on its microplate readers. The Atmospheric Control Unit (ACU) for the CLARIOstar is a unique microprocessor-controlled unit that independently regulates both CO2 and O2 inside the microplate reader. Alternatively, the Gas Vent is a positive pressure gas purge through which the internal atmosphere of the microplate reader can be replaced.

Incubation and shaking

Shaking and incubation allow users to mix the well content and easily run measurements at elevated temperatures. The incubator controls the air temperature in the measurement chamber from room temperature up to 45°C, 60°C or 65°C. BMG LABTECH microplate readers are equipped with orbital, double-orbital or linear shaking with definable intensity, duration and direction of motion. These features are available on all BMG LABTECH plate readers.

Reagent injectors

Many of today's most popular assays such as enzyme kinetics, calcium flux, and dual luciferase require the ability to monitor a signal during and after the addition of a reagent. All BMG LABTECH readers, with the exception of the SPECTROstar Nano, can be equipped with up to two reagent injectors. Injectors enable reagent delivery to any plate format from 6 to 384 wells.
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