Atmospheric Control Unit

Enhanced cell-based assays


The Atmospheric Control Unit (ACU) for the CLARIOstar Plus, VANTAstar, Omega series and NEPHELOstar Plus is the ideal solution for live cell-based applications, from standard cell growth to hypoxic assays or pH control. The ACU provides a complete solution to fully and independently regulate both O2 and CO2 gas levels within the microplate reader chamber. From standard proliferation to hypoxic or cytotoxicity assays, the ACU provides the optimal environment for any live cell assay.

In combination with temperature control, shaking options, and bottom reading detection, the ACU offers a versatile walk-away solution for long-term cell-based assays.

Unique gas ramping feature

As a unique feature within plate readers, the CLARIOstar Plus with ACU offers the capability to run O2 and CO2 gas ramps. For instance, the ACU can deprive O2 and then rapidly re-oxygenate back to physiological conditions, keeping meanwhile steady CO2 levels. This capability enhances live cell-based assays and supports ischemia-reperfusion research, as disease models such as ischemia-reperfusion can be reproduced in vitro in a microplate reader.

Microplate reader accessory Atmospheric Control Unit (ACU)


  • O2 control range: 0.1 - 20%, 1-20% VANTAstar
  • CO2 control range: 0.1 - 20%, 1-20% VANTAstar
  • Gas ramping function (CLARIOstar Plus only)
  • Gas value trackability in MARS Data Analysis Software (CLARIOstar Plus only)
  • LCD touchscreen with intuitive user interface and gas concentration curve display
  • Up to 10 user-definable presets
  • Superior valve control for minimal gas consumption
  • Integrated gas pressure regulators and sensors with acoustic alarm
  • Altitude correction for accurate gas regulation


  • Proliferation assays and cell viability
  • Migration and invasion studies
  • Hypoxia
  • Ischemia/reperfusion (CLARIOstar Plus only)
  • Angiogenesis
  • Cell Cytotoxicity studies
  • Viral uptake
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