Advanced Assay Stability

A stable detection environment, unaffected by external environmental changes from the first plate to the last.

 

 

BMG LABTECH is a leading global manufacturer of innovative, high-quality, and reliable microplate reader instrumentation.

 

 

 

What we do?

Multi-mode microplate readers

Multi-mode microplate readers

Multi-mode microplate readers are capable of operating in two or more detection modes. Typically, they combine an absorbance plate reader, a luminescence plate reader, and a fluorescence plate reader. In addition, the range can be enhanced with more advanced detection modes like TRF, TR-FRET, fluorescence polarization and AlphaScreen/AlphaLISA.

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Absorbance microplate readers

Absorbance microplate readers

An absorbance microplate reader detects the light photons absorbed by a sample present in a microplate, when exposed to light at a specific wavelength. Compared to a spectrophotometer that measures one sample at a time in a cuvette, an absorbance microplate reader can measure the same assay in higher throughput.

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Fluorescence microplate readers

Fluorescence microplate readers

A fluorescence plate reader detects the light emitted by a fluorescent sample present in a microplate upon excitation with light at a specific wavelength. Fluorescence plate readers are used for fluorescence intensity and FRET detection and are available as single- or multi-mode readers, when combined with absorbance and/or luminescence.

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Luminescence microplate readers

Luminescence microplate readers

A luminescence microplate reader detects the light emitted by chemical, bio-chemical or enzymatic reactions. Luminescence plate readers are used for flash, glow assays and BRET detection and are available as single- or multi-mode readers, when combined with absorbance and/or fluorescence.

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Nephelometers

Nephelometers

A nephelometer microplate reader is an instrument dedicated to the measurement of the turbidity of a sample, usually caused by the presence of insoluble particles suspended in a liquid. Nephelometer microplate readers measure the light scattering generated by these particles and are used for solubility or aggregation studies.

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What‘s new at BMG LABTECH

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Biology from the deep-sea: engineering the brightest proteins from the depths

Find out how proteins from deep-sea luminescent organisms are useful for measurements on microplate readers.
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Peptidic inhibitors of α-Synuclein preventing Parkinson’s disease-associated fibrilization and cytotoxicity

Read here how peptidic inhibitors of α-Synuclein nucleation and fibril elongation can be evaluated on microplate readers.
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Production of peroxynitrite by cancer-associated immune cells can be detected with a fluorescence-based assay

The fluorescent sensor PS3 can be used to monitor immunosuppression in the tumor microenvironment by detecting peroxynitrite production. Find out more here.
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How to choose the best microplate colour for my assay

Unsure about the choice of microplate colour? Find out how plate colour affects the results in different detection modes and make an informed decision for your assay.
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Ann-Cathrin Volz

She comes from a small town near our headquarters, meet Ann-Cathrin a passionate crafter.
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Role of second messengers and signal transmission in the cell

Second messengers play a pivotal role in signal transduction events in cells. But how do you measure these small, transiently lived molecules and how can microplate readers help?
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Mimicking the in vivo environment of atherosclerotic vascular disease

Atherosclerotic vascular disease is one of the leading causes of death globally. Here we explore some of the research options available to scientists to tackle this significant threat to public health.
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Differential binding of ∆9-tetrahydrocannabinol derivatives to type 1 cannabinoid receptors (CB1)

Looking for alternative acceptor fluorophores in TR-FRET attempts? Read here how CELT-335 was successfully used in a Cannabinoid competition binding assay at CB1.
Testimonials

"Most common absorbance-, luminescence- and fluorescence-based assays are able to be run without having to hunt high and low"

Dr Crystale Lim Siew Ying (Associate Professor/Deputy Dean, Faculty of Applied Sciences of UCSI University, Malaysia)
Dr Crystale Lim Siew Ying (Associate Professor/Deputy Dean, Faculty of Applied Sciences of UCSI University, Malaysia)

"We need to get consistent, high-quality data regardless of location […] for that reason, we chose the PHERAstar FSX"

Dr Ian Waddell (Executive Director Biology, Charles River Laboratories, UK)
Dr Ian Waddell (Executive Director Biology, Charles River Laboratories, UK)

"The PHERAstar is a very high-end instrument which is very good for high-throughput screening and is the most sensitive instrument I have tested for BRET."

Dr Kevin Pfleger (Associate Professor, Harry Perkins Institute of Medical Research, The University of Western Australia, Australia)
Dr Kevin Pfleger (Associate Professor, Harry Perkins Institute of Medical Research, The University of Western Australia, Australia)

"The CLARIOstar shows a fantastic performance with fluorescence, luminescence and UV measurements […] We are therefore very satisfied with this device and we strongly recommend it"

Dr Alfredo Castello-Palomares (Group leader, Oxford University, UK)
Dr Alfredo Castello-Palomares (Group leader, Oxford University, UK)

"The CLARIOstar microplate reader is essential to all the research we do […] Just love it!"

Scott Snipas (Research Coordinator, Sanford Burnham Prebys Medical Discovery Institute, USA)
Scott Snipas (Research Coordinator, Sanford Burnham Prebys Medical Discovery Institute, USA)
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