Advanced Assay Stability

A stable detection environment, unaffected by external environmental changes from the first plate to the last.

 

 

BMG LABTECH is a leading global manufacturer of innovative, high-quality, and reliable microplate reader instrumentation.

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What we do?

Multi-mode microplate readers

Multi-mode microplate readers

Multi-mode microplate readers are capable of operating in two or more detection modes. Typically, they combine an absorbance plate reader, a luminescence plate reader, and a fluorescence plate reader. In addition, the range can be enhanced with more advanced detection modes like TRF, TR-FRET, fluorescence polarization and AlphaScreen/AlphaLISA.

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Absorbance microplate readers

Absorbance microplate readers

An absorbance microplate reader detects the light photons absorbed by a sample present in a microplate, when exposed to light at a specific wavelength. Compared to a spectrophotometer that measures one sample at a time in a cuvette, an absorbance microplate reader can measure the same assay in higher throughput.

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Fluorescence microplate readers

Fluorescence microplate readers

A fluorescence plate reader detects the light emitted by a fluorescent sample present in a microplate upon excitation with light at a specific wavelength. Fluorescence plate readers are used for fluorescence intensity and FRET detection and are available as single- or multi-mode readers, when combined with absorbance and/or luminescence.

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Luminescence microplate readers

Luminescence microplate readers

A luminescence microplate reader detects the light emitted by chemical, bio-chemical or enzymatic reactions. Luminescence plate readers are used for flash, glow assays and BRET detection and are available as single- or multi-mode readers, when combined with absorbance and/or fluorescence.

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Nephelometers

Nephelometers

A nephelometer microplate reader is an instrument dedicated to the measurement of the turbidity of a sample, usually caused by the presence of insoluble particles suspended in a liquid. Nephelometer microplate readers measure the light scattering generated by these particles and are used for solubility or aggregation studies.

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What‘s new at BMG LABTECH

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Competition assay using Fluorescence Polarization to determine the Residence Times for Calcitonin and AMYR agonist, AM833

Inform yourself here about the benefits of an alternative to (TR-)FRET-/BRET-based competition assays using FP for the determination of kon and koff of ligand/receptor interaction.
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How to reduce data variability in heterogenous cell samples

Your cell samples are distributed unevenly, and you fear that you are measuring off-target? Read here how to capture all cells in your microplate reader measurements.
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How to reduce autofluorescence in cell-based assays

Is autofluorescence giving you a hard time when measuring cell-based assays? Read here where autofluorescence originates from and how to work around it.
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Neuronal cell death and neurodegenerative disease

Neurodegenerative disease ultimately leads to the death of neurons as neuronal functions deteriorate. Find out how microplate readers can be used to study neuronal cell death and its link to neurodegenerative disease.
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Cell-free extract protein synthesis: Rapid single vessel DNA assembly and protein production in microliter scale

Read here, how protein synthesis in cell-free extracts can be used to rapidly screen for protein variants in low-volume single vessel reactions with the CLARIOstar Plus.
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PROTACs: proteolysis-targeting chimeras

PROTACs are small, readily designed molecules that target unwanted proteins to the cell’s ubiquitin-proteasome system for degradation. Find out how microplate readers can advance PROTAC research.
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Mitochondrial dysfunction and neurodegenerative disease

The disruption of mitochondrial function is linked to neurodegenerative diseases. Find out how microplate readers advance research into mitochondrial dysfunction and neurodegenerative diseases.
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Misfolded proteins and neurodegenerative diseases

The way proteins misfold and aggregate is linked to many neurodegenerative diseases. Find out how microplate readers can help advance research into protein misfolding.
Testimonials

"Most common absorbance-, luminescence- and fluorescence-based assays are able to be run without having to hunt high and low"

Dr Crystale Lim Siew Ying (Associate Professor/Deputy Dean, Faculty of Applied Sciences of UCSI University, Malaysia)
Dr Crystale Lim Siew Ying (Associate Professor/Deputy Dean, Faculty of Applied Sciences of UCSI University, Malaysia)

"We need to get consistent, high-quality data regardless of location […] for that reason, we chose the PHERAstar FSX"

Dr Ian Waddell (Executive Director Biology, Charles River Laboratories, UK)
Dr Ian Waddell (Executive Director Biology, Charles River Laboratories, UK)

"The PHERAstar is a very high-end instrument which is very good for high-throughput screening and is the most sensitive instrument I have tested for BRET."

Dr Kevin Pfleger (Associate Professor, Harry Perkins Institute of Medical Research, The University of Western Australia, Australia)
Dr Kevin Pfleger (Associate Professor, Harry Perkins Institute of Medical Research, The University of Western Australia, Australia)

"The CLARIOstar shows a fantastic performance with fluorescence, luminescence and UV measurements […] We are therefore very satisfied with this device and we strongly recommend it"

 Dr Alfredo Castello-Palomares (Group leader, Oxford University, UK)
Dr Alfredo Castello-Palomares (Group leader, Oxford University, UK)

"The CLARIOstar microplate reader is essential to all the research we do […] Just love it!"

Scott Snipas (Research Coordinator, Sanford Burnham Prebys Medical Discovery Institute, USA)
Scott Snipas (Research Coordinator, Sanford Burnham Prebys Medical Discovery Institute, USA)
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