Biochemistry

The complexity of life is based on chemical processes within organisms. Biochemistry studies these chemical reactions and our readers are the tools for your discoveries.

Methods that answer biochemical question are as varied as the chemical processes in living organisms. They cover simple protein quantification assays such as Bradford or Lowry assay to adjust protein extracts for further analysis, as well as enzyme activity assays helping to find inhibitory and accelerating conditions. These assays benefit from BMG LABTECH´s kinetic read options, an Enhanced Dynamic Range for high intensity variations in a measurement and a suite of enzyme kinetic analysis options.


An achievement of the past 20 years has been the multitude of protein interaction assays that can be carried out in 96 to 1536 well plates. They replace lengthy or radioactive procedures and facilitate the screening for potential active substances.


BMG LABTECH microplate readers measure all these assays. They not only provide highest sensitivity and throughput, if necessary, they further assist in developing your own assays and adapting existing methods to your specific target.

Resources

Search our Resources section for information about specific applications, literature citations, videos, blog articles and many other publications. Many of the resources provided are associated with current and previous instrument models and versions.

    Neurodegenerative disease research
    April 02, 2020

    Neurodegenerative disease research

    Today, life expectancy in developed countries is well above 80 years of age, but with a longer life expectancy comes a higher chance of developing a neurodegenerative disease, such as Alzheimer’s disease, Parkinson’s disease and dementia. As these disorders progress, they become increasingly debilitating until full-time care is required. Unfortunately, the etiology of these diseases is still not fully understood, and most drugs only treat symptoms. With life expectancy on the rise, it is important to further our understanding of these conditions and develop new treatments. 

    Read more
    • β-Turn mimetic synthetic peptides as amyloid-β aggregation inhibitors

      Deike, S;Rothemund, S;Voigt, B;Samantray, S;Strodel, B;Binder, WH;[2020]

      Bioorg. Chem.

      Read article
    • Kinetic Analysis of the Early Signaling Steps of the Human Chemokine Receptor CXCR4

      Perpiñá-Viciano, C;Işbilir, A;Zarca, A;Caspar, B;Kilpatrick, LE;Hill, SJ;Smit, MJ;Lohse, MJ;Hoffmann, C;[2020]

      Mol. Pharmacol.

      Read article
    • USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation

      Rusilowicz-Jones, EV;Jardine, J;Kallinos, A;Pinto-Fernandez, A;Guenther, F;Giurrandino, M;Barone, FG;McCarron, K;Burke, CJ;Murad, A;Martinez, A;Marcassa, E;Gersch, M;Buckmelter, AJ;Kayser-Bricker, KJ;Lamoliatte, F;Gajbhiye, A;Davis, S;Scott, HC;Murphy, E;[2020]

      Life Sci Alliance

      Read article
    • Anti-tumor effects of mevalonate pathway inhibition in ovarian cancer

      Göbel, A;Zinna, VM;Dell'Endice, S;Jaschke, N;Kuhlmann, JD;Wimberger, P;Rachner, TD;[2020]

      BMC Cancer

      Read article
    • Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity

      Shin, D;Mukherjee, R;Grewe, D;Bojkova, D;Baek, K;Bhattacharya, A;Schulz, L;Widera, M;Mehdipour, AR;Tascher, G;Geurink, PP;Wilhelm, A;van der Heden van Noort, GJ;Ovaa, H;Müller, S;Knobeloch, KP;Rajalingam, K;Schulman, BA;Cinatl, J;Hummer, G;Ciesek, S;Dikic[2020]

      Nature

      Read article