NOVOstar - Cell-based fast kinetic microplate reader with integrated liquid transfer for rapidly screening up to 384 different analytes

In the past, cell-based assays required the use of expensive HTS equipment, which lead to limited accessibility for scientists in the assay development stage. In order to reduce this bottleneck, BMG LABTECH developed the NOVOstar, an exciting microplate reader for screening a large number of compounds in fast kinetic, cell-based assays and research development. The NOVOstar is a compact microplate reader offering five detection modes in a unique combination with an integrated pipettor system for automated assembly and instantaneous reading of assays in microplate formats up to 384-well.

• Fluorescence Polarization


• Fluorescence Intensity - including FRET and multilable applications


• Time-Resolved Fluorescence - including DELFIA^®


• Absorbance - UV/Vis with path length correction


• High-Performance Luminescence (flash and glow) - DLReady^TM certified

Choose Instrument
PHERAstar FS
PHERAstar Plus
POLARstar Omega
FLUOstar Omega
LUMIstar Omega
SPECTROstar Omega
POLARstar OPTIMA
FLUOstar OPTIMA
FLUOstar OPTIMA ABS
FLUOstar OPTIMA F
FLUOstar OPTIMA FL
LUMIstar OPTIMA
NOVOstar
NEPHELOstar
RUBYstar

• Dual Microplate Carrier: Accommodates one reagent plate and one sample plate, allowing you to rapidly screen up to 384 different analytes in one test run.


• Integrated Pipettor System: The system can be used for plate-to-plate and tube-to-plate liquid transfer, aspirating, dispensing, or mixing fluids within a microplate well. Very small amounts of substance (<1 µL) and individual volumes can be added followed by instantaneous reading.


• Additional Reagent Stations and Reagent Injectors: The pipettor system has access to 3 additional reagent stations (e.g. standard agonist/antagonists, ionophore, washing, etc.) and you can use any of the two injectors for dispensing these and other standard reagents choosing individual volumes for each well.


• User-defined Kinetic Sampling: The NOVOstar is one of the few microplate readers that can measure kinetic events with a resolution of 20 ms, allowing for calcium uptake assays to be performed with great precision. Furthermore, the control software allows the user to define variable sampling rates throughout the test run so that data evaluation can be simplified.


• Multi-wavelength Detection: NOVOstar uses a xenon flash lamp that allows measurement up to eight excitation/emission pairs in each well. This allows reading of dual excitation fluorophores such as Fura-2 with speed and convenience.


• Precise Temperature Control: The NOVOstar microplate reader incorporates BMG LABTECH's proprietary heating plates situated above and below the entire plate movement area providing for uniform incubation up to 45°C.


• Real-time Data Observation: Assay progress can be observed with the real-time graphics feature showing the measurment data either as a numerical value, color gradient, or X-Y plot.

• Ca2+ uptake (Application Note104, Application Note 107, Application Note 157)


• Membrane potential studies (Application Note 123)


• Intracellular pH
• Intracellular cAMP, e.g. FRET based assay with CFP (article)


• Measurement of intracellular ionic changes


• Cell proliferation assay, e.g. with Alamar Blue (article)


• Fluorescent reporter gene assays, e.g. GFP (article), YFP/CFP FRET-based assay (Application Note 163)


• FRET-based assay, e.g. SUMO protease activity with YFP and enhanced CFP as donor-acceptor pair (Application Note 163) FRET-based voltage sensor probes (Application Note 123)


• Dual Luciferase Reporter Assay, e.g. determination of siRNA silencing efficiency (article)


• Cell adhesion assay, e.g. with calcein AM (article)


• Enzyme activity, e.g. 2-OG hydroxylase enzymes (Application Note 132), histone deacetylase inhibition in cancer research (article)


• ELISA (article)

DELFIA is a registered trademark of Perkin Elmer Inc.
DLReady is a trademark of Promega Corp.
Windows Vista is a trademark of Microsoft Corporation.