Atmospheric Control Unit

Enhanced cell-based assays

The Atmospheric Control Unit (ACU) for the CLARIOstar microplate reader is the ideal solution for live cell-based applications, from standard cell growth to hypoxic assays or pH control. The ACU provides a complete solution to fully and independently regulate both O2 and CO2 gas levels within the microplate reader chamber. From standard proliferation to hypoxic or cytotoxicity assays, the ACU provides the optimal environment for any live cell assay.


Unique gas ramping feature


As a unique feature within plate readers, the CLARIOstar with ACU offers the capability to run O2 and CO2 gas ramps. For instance, the ACU can deprive O2 and then rapidly re-oxygenate back to physiological conditions, keeping meanwhile steady CO2 levels. This capability enhances live cell-based assays, as disease models such as ischemia/reperfusion can be reproduced in vitro in a microplate reader.


In combination with temperature control, shaking options, and bottom reading detection, the ACU provides a versatile walk-away solution for long-term cell-based assays.


  • O2 control range: 0.1 - 20%
  • CO2 control range: 0.1 - 20%
  • Gas ramping function (e.g.: oxygen deprivation and reoyxgenation ramp)
  • LCD touchscreen with intuitive user interface and gas concentration curve display
  • Up to 10 user-definable presets
  • Superior valve control for minimal gas consumption
  • Integrated gas pressure regulators and sensors with acoustic alarm
  • Altitude correction for accurate gas regulation


  • Proliferation assays and cell viability
  • Migration and invasion studies
  • Hypoxia and ischemia/reperfusion
  • Angiogenesis
  • Cytotoxicity studies
  • Viral uptake

Compatible readers

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