Scientific talk library
Our team regularly hosts new talks about current topics. If you would like to share your research results and experiences with your microplate reader in a talk, please contact us.
Using the TRUPATH BRET platform to analyse GPCR biased agonism
TRUPATH is a BRET-based platform that enables to monitor discrete GPCR-G protein coupling and can facilitate the discovery of drugs biased towards desired G protein effectors.
Current microplate-based interaction assays for drug discovery
In this talk we highlight how advanced detection technologies such as NanoBRET and TR-FRET can be used in high-throughput drug screening.
The ORAC assay: industrial and academic relevance
Shalini Markandan, Forest Research Institute of Malaysia, discusses misconceptions about ORAC, provides a better way to interpret data, highlights challenges for ORAC beginners, and shows how BMG LABTECH microplate readers can help.
COVID targets in the crosshairs: Achieving unparalleled quality and speed
In this talk, Daniel Thomas, Head of Discovery Biology at Arctoris, describes the acceleration of onboarding and validation of three critical assays targeted on SARS-CoV-2 drug discovery
Repurposing FDA-approved drugs for treatment of COVID-19
Ahlam Ali from Queen’s University Belfast, UK shows results from a screen for antiviral and anti-inflammatory activity against SARS-CoV-2 using a drug repurposing approach.
Real-time monitoring of redox changes in cells with a microplate reader
This talk answers the question whether redox sensitive probes can be used to monitor redox enzyme activity.
THUNDER cell signaling assays performed on the CLARIOstar Plus
In this tutorial, Jaime Padrós of BioAuxilium Research introduces a new line of ready-to-use cell signaling assay kits based on their enhanced proprietary TR-FRET platform.
When viral RNA met the host cell: The importance of cellular RNA-binding proteins in virus infection
In this webinar, Dr. Alfredo Castello (University of Glasgow) will describe a recently developed approach, called viral RNA interactome capture (vRIC)
Converting endpoint microplate assays to real-time data output
Dan Close and Mark Wienhold from 490 Biotech talk in this scientific talk about how to convert endpoint microplate assays to real-time data output.
Kinetic or endpoint monitoring of protein kinase and phosphatase activity
Erik Schaefer, CEO of AssayQuant Technologies talks about the monitoring of protein kinase and phosphatase activity using kinetic or endpoint formats
Kinetics in Drug Discovery
Martin Redhead (UCB) discusses the use and impact of kinetic binding methods across the drug discovery pipeline.
Protein analysis, instrumentation and applications
In this talk, Support Specialist Joko Logis introduces the BMG LABTECH microplate readers and focuses particularly on protein quantification assays.
Miniaturising screening assays: a case study
Dr Céline Legros explains how you can successfully downscaling screening assays with the PHERAstar.
Simulating ischemia reperfusion injury in vitro as a potential method for drug screening
Dr. Ben Allsop from UCL Drug Discovery Group talks at SLAS 2019 about simulating ischemia-reperfusion injury and how the new CLARIOstar Plus with ACU can help at this research.
GPCR bias: a kinetic, dual-channel fluorescence method to simultaneously measure arrestin and G-protein second messenger responses
In this tutorial Montana Molecular describes a new approach that takes advantage of the dual channel fluorescence detection.
Cell-based and biochemical high-throughput screening in 1536-well plates
In this scientific talk the speakers talk about cell-based and biochemical high-throughput screening.
Kinetic characterisation of covalent inhibitors on the PHERAstar
This scientific talk covers the recent discovery of a new covalent inhibitor targeting the hitherto undruggable cancer target USP7.
A TR-FRET approach to measure the kinetics of ligand-receptor binding and its application of fragment screening
Leave radioactive assays behind: PHERAstar provides temporal resolution to determine kon and koff rates by TR-FRET kinetics
Real-time cell health assays deliver better data with less effort
Never again miss the point of a cellular reaction: CLARIOstar measures viability and toxicity in real-time
Defining physiological normoxia in cultured cells for translation to animal models and man
Learn how the CLARIOstar with ACU replicates in vivo oxygen conditions to increase the significance of your data
Real-time profiling of receptor pharmacology
Get inspired how to use NanoBRET to monitor G-protein binding, receptor internalization or receptor heteromerization
Real time detection of G-protein coupled receptors in living cells
How the CLARIOstar is used to monitor multiple second messengers in real-time
Optimizing sensitivity and specifity in the RT- QUiC assay
Tips and tricks to set up and analyze amyloid seeding assays
The kinetics of drug binding
The speed of the PHERAstar enables kinetic TR-FRET measurements to determine kon and koff rates
Enhanced protein-protein Interactions in living cells using the NanoBRET assay & CLARIOstar
Find out why the CLARIOstar’s LVF monochromator is perfectly suited for NanoBRET measurements