Blog

BMG LABTECH U.S. hosted the first User Group Meeting in San Diego, CA. Fifty PHERAstar and CLARIOstar users enjoyed a day filled with scientific talks, networking opportunities and German delicacies. Scientists had the chance to share with other users how they use their BMG LABTECH microplate readers and learn from BMG staff how to optimize assays and get the most out of BMG’s software.

No life science or diagnostic lab can live without it: the ELISA assay. The article explains the principle of ELISA assays and presents variables that determine the sensitivity and precision of your measurements.

From an engineer’s point of view, biology has a frustrating lack of standardized parts. Usually, a microprocessor designed in drafted software is produced and functions exactly the way it’s supposed to once it has been stamped, fabbed and machined. The goal of Synthetic Biology is to be able to provide solutions to problems in the same way an electronic circuit can be engineered.

Meat scientists strive to improve and grow the red meat sector and doing so, remain committed to optimising both the consumer’s experience and industry efficiencies. 

Coronary heart disease (CHD) is a complex condition that affects millions of people worldwide. There are many pathways and processes involved in the pathogenesis of this disease, and attempting to mimic these interactions in laboratory environments can prove troublesome. This blog article explains how ischemia and reperfusion models can be used to examine the complications of CHD and discover potential drug targets.

Despite some criticism biofuels are highly regarded as the best alternative to help maintain the transport sector globally and assist in reduction of CO2 emissions. The basic argument for biofuels is very logical indeed; they are derived from plant material that are working to remove carbon from the atmosphere so they should be reducing the carbon footprint or at least be neutral in this respect. But as is usually the case, especially when we are discussing the environment, things are not that simple.

Whether studying a particular disease or a particular tissue the relevance of the data obtained from cell-based assays are always going to be affected by how closely the conditions used in the study recapitulate the physiological environment in vivo.

The first European PHERAstar User Meeting took place at the Pivot Park in Oss, the Netherlands, from May 9th to 10th. 

We read with great interest the recent Cell paper entitled ‘Pharmacogenomics of GPCR Drug Targets’. The authors used a PHERAstar FS to monitor a BRET assay that looked at activation of GPCR.

Second messengers are intracellular molecules that transmit signals triggered by extracellular "first" messengers. We explain how fast second messenger responses are measured on a microplate reader.