Powerful and most sensitive HTS plate reader
The PHERAstar® FSX is our latest, most sensitive multi-mode reader for high-throughput screening, combining this sensitivity with fast read times. Thanks to the unique Optic Module system, Simultaneous Dual Emission, UV/vis spectrometer, and dedicated AlphaScreen® and TRF lasers, the PHERAstar FSX will perform your assay with ease and speed, even in 3456-well microplates.
No longer worry about installing filters and dichroics: the PHERAstar FSX comes with easy-to-handle, assay-optimized Optic Modules which contain all application-specific filters, mirrors, dichroics and/or polarizers, and are automatically recognized by the plate reader. In addition, the PHERAstar FSX is equipped with four matched and assay-optimized photomultiplier tubes (PMTs) which are automatically selected for the relevant detection mode. You can also measure assays with two emission wavelengths at the same time thanks to the Simultaneous Dual Emission.
For HTS automation purposes, the PHERAstar FSX offers improved robotic integration capabilities and multi-user control.
- The most sensitive reader in fluorescence intensity and polarization
- The only plate reader with 5 assay-dedicated detectors
- Simultaneous Dual Emission, including for Alpha Technology
- 9 decades luminescence dynamic range
- Dedicated AlphaScreen®/AlphaLISA®/AlphaPlex™ laser
- New generation TRF-laser
- Top and bottom focal height adjustment
- High-precision injectors with simultaneous reagent injection and detection
- High-speed absorbance measurements
Novel aggregation-specific fluorogen monitors prefibrillar protein aggregation by fluorescence polarisation (FP)Manjeet Kumar (1) , Yuning Hong (2,3) , David C. Thorn (1) , Heath Ecroyd (4) , John A. Carver (1), (1) Research School of Chemistry, The Australian National University, Australia , (2) Department of Chemistry and Physics, La Trobe Institute for Molecular Science, La Trobe University, Australia , (3) School of Chemistry, The University of Melbourne, Australia , (4) School of Biological Sciences, Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong, Australia, 07/2018
Cell-based assay detects residual nonsteroidal anti-inflammatory drugs (NSAIDs) in effluent of municipal wastewater treatmentK. Bernhard , C. Stahl , R. Martens , M. Frey, SIZ Zellkulturtechnik, c/o Hochschule Mannheim, Mannheim, Germany, 06/2018
PHERAstar measures AlphaScreen assay to develop selective inhibitors for the human YEATS domainsThomas Christott , Carmen Coxon , James Bennett , Charline Giroud , Octovia Monteiro , Oleg Fedorov, Structural Genomics Consortium, University of Oxford, UK, 04/2018
Cell-based assay detects residual β-blocker substances in effluent of municipal wastewater treatment plantsK. Bernhard , C. Stahl , R. Martens , M. Frey, SIZ Zellkulturtechnik, c/o Hochschule Mannheim, Mannheim, Germany, 03/2018
FRET sensor assesses ATP levels in living plants experiencing low oxygen conditionsStephan Wagner (1,2) , Philippe Fuchs (1,2) , Thomas Nietzel (1,2) , Marlene Elsässer (1,2) , Markus Schwarzländer (1,2), (1) Institute of Plant Biology and Biotechnology, University of Münster, Germany , (2) Institute of Crop Science and Resource Conservation (INRES), University of Bonn, Germany, 02/2018