レーザー光源を搭載した唯一の光散乱測定プレートリーダーは、創薬における化合物溶解度スクリーニングに合わせて設計されました。NEPHELOstar Plusは光散乱によってウェル内に浮遊している微細粒子を検出し、濁度測定・薬物溶解度スクリーニング、タンパク質結合のモニタリング、微生物の生育曲線測定、石油のプロセスコントロールなどに用いられています。

Detection Modes

NEPHELOstar Plus

NEPHELOstar Plusは高エネルギーのレーザーダイオードを光源として搭載しています。これにより、同じように透過光を検出する従来の吸光度測定と比べて、30倍以上も感度が良くなりました。その測定スピード・柔軟性・パフォーマンスにより、NEPHELOstar Plusは唯一無二の光散乱測定プレートリーダーであるといえます。

特徴

レーザー強度・レーザー径はアッセイに合わせて任意に可変
384wellプレート対応
45℃までの温度制御
直線・円回転・８の字シェイキング
試薬注入と検出を同時に行う高精度インジェクター（2chまで)
BMG専用スタッカー及び各社ロボットシステムにインテグレーション可能

Automation

Automation is a key feature in high-throughput screening. Several BMG LABTECH microplate readers have been successfully integrated into various robotic systems. Since all instruments have the same x-y dimensions and plate out/in position, once automation has been designed for one BMG LABTECH reader, the solution will work for all. All plate readers can be controlled through ActiveX or DDE interfaces. Moreover, the ASCII data output is the most versatile in the industry and works with most LIMS and automation platforms.

Gas Vent

BMG LABTECH offers two forms of gas control on its microplate readers. The Atmospheric Control Unit (ACU) for the CLARIOstar is a unique microprocessor-controlled unit that independently regulates both CO₂ and O₂ inside the microplate reader. Alternatively, the Gas Vent is a positive pressure gas purge through which the internal atmosphere of the microplate reader can be replaced.

Incubation and shaking

Shaking and incubation allow users to mix the well content and easily run measurements at elevated temperatures. The incubator controls the air temperature in the measurement chamber from room temperature up to 45 °C or 65 °C. BMG LABTECH microplate readers are equipped with orbital, double-orbital or linear shaking with definable intensity, duration and direction of motion. These features are available on all BMG LABTECH plate readers.

Open PHERAstar showing pumps for reagent injection

Reagent injectors

Many of today's most popular assays such as enzyme kinetics, calcium flux, and dual luciferase require the ability to monitor a signal during and after the addition of a reagent.
All BMG LABTECH readers, with the exception of the SPECTROstar Nano, can be equipped with up to two built-in reagent injectors. Injectors enable reagent delivery to any plate format from 6 to 384 wells.