How is the limit of detection (LOD) calculated for BMG LABTECH microplate reader specifications?

July 16, 2012

BMG LABTECH provides realistic, real-world information about the measurement capabilities of its readers.

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Dr. EJ Dell
PhD, Sales Manager Northwest
BMG LABTECH USA

In 2000, BMG LABTECH was among the first microplate reader companies to use the International Union of Pure an Applied Chemistry (IUPAC) definitions for limit of detection (LOD) and limit of quantitation (LOQ). These two metrics quantify the sensitivity of a microplate reader and provide a statistical method to rate performance.

 

LOD/LOQ results are hard to compare from company to company because there is no regulating body that specifies the exact quantifiable methods for the various modes in a microplate reader. Therefore, BMG LABTECH provides conservative LOD/LOQ data for its microplate readers. BMG LABTECH guarantees that their published specifications for any of their production instruments will be able to be duplicated using normal methods and procedures.

 

BMG LABTECH uses the following equations to determine its specifications for sensitivity:

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