-
Structure of AMH bound to AMHR2 provides insight into a unique signaling pair in the TGF-β family
Hart, KN;Stocker, WA;Nagykery, NG;Walton, KL;Harrison, CA;Donahoe, PK;Pépin, D;Thompson, TB; [2021]
Proceedings of the National Academy of Sciences of the United States of America 118(26)
-
Proteasomal conformation controls unfolding ability
Cresti, JR;Manfredonia, AJ;Bragança, CE;Boscia, JA;Hurley, CM;Cundiff, MD;Kraut, DA; [2021]
Proceedings of the National Academy of Sciences of the United States of America 118(25)
-
Identification of a novel PHGDH covalent inhibitor by chemical proteomics and phenotypic profiling
Chen, C;Zhu, T;Liu, X;Zhu, D;Zhang, Y;Wu, S;Han, C;Zhang, H;Luo, J;Kong, L; [2021]
Acta Pharmaceutica Sinica B
-
Phosphoproteomic identification of ULK substrates reveals VPS15-dependent ULK/VPS34 interplay in the regulation of autophagy
Mercer, TJ;Ohashi, Y;Boeing, S;Jefferies, HBJ;De Tito, S;Flynn, H;Tremel, S;Zhang, W;Wirth, M;Frith, D;Snijders, AP;Williams, RL;Tooze, SA; [2021]
The EMBO journal e105985
-
Nuclear compartmentalization of TERT mRNA and TUG1 lncRNA is driven by intron retention
Dumbović, G;Braunschweig, U;Langner, HK;Smallegan, M;Biayna, J;Hass, EP;Jastrzebska, K;Blencowe, B;Cech, TR;Caruthers, MH;Rinn, JL; [2021]
Nature communications 12(1) 3308
-
The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation
Xu, X;Ni, K;He, Y;Ren, J;Sun, C;Liu, Y;Aladjem, MI;Burkett, S;Finney, R;Ding, X;Sharan, SK;Muegge, K; [2021]
Nature communications 12(1) 3520
-
An immune-competent, replication-permissive Syrian Hamster glioma model for evaluating Delta-24-RGD oncolytic adenovirus
Phillips, LM;Li, S;Gumin, J;Daou, M;Ledbetter, D;Yang, J;Singh, S;Parker Kerrigan, BC;Hossain, A;Yuan, Y;Gomez-Manzano, C;Fueyo, J;Lang, FF; [2021]
Neuro-oncology
-
Modular cell-assembled adipose matrix-derived bead foams as a mesenchymal stromal cell delivery platform for soft tissue regeneration
Morissette Martin, P;Walker, JT;Kim, KJ;Brooks, CR;Serack, FE;Kornmuller, A;Juignet, L;Hamilton, AM;Dunmore-Buyze, PJ;Drangova, M;Ronald, JA;Flynn, LE; [2021]
Biomaterials 275 120978
-
Immunotherapy using IgE or CAR T cells for cancers expressing the tumor antigen SLC3A2
Pellizzari, G;Martinez, O;Crescioli, S;Page, R;Di Meo, A;Mele, S;Chiaruttini, G;Hoinka, J;Batruch, I;Prassas, I;Grandits, M;López-Abente, J;Bugallo-Blanco, E;Ward, M;Bax, HJ;French, E;Cheung, A;Lombardi, S;Figini, M;Lacy, KE;Diamandis, EP;Josephs, DH;Spic [2021]
Journal for immunotherapy of cancer 9(6)
-
Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance
Zatreanu, D;Robinson, HMR;Alkhatib, O;Boursier, M;Finch, H;Geo, L;Grande, D;Grinkevich, V;Heald, RA;Langdon, S;Majithiya, J;McWhirter, C;Martin, NMB;Moore, S;Neves, J;Rajendra, E;Ranzani, M;Schaedler, T;Stockley, M;Wiggins, K;Brough, R;Sridhar, S;Gulati, [2021]
Nature communications 12(1) 3636
-
CRISPR-Associated Primase-Polymerases are implicated in prokaryotic CRISPR-Cas adaptation
Zabrady, K;Zabrady, M;Kolesar, P;Li, AWH;Doherty, AJ; [2021]
Nature communications 12(1) 3690
-
Unravelling cytosolic delivery of cell penetrating peptides with a quantitative endosomal escape assay
Teo, SLY;Rennick, JJ;Yuen, D;Al-Wassiti, H;Johnston, APR;Pouton, CW; [2021]
Nature communications 12(1) 3721
-
Phenotypic manifestation of α-synuclein strains derived from Parkinson\'s disease and multiple system atrophy in human dopaminergic neurons
Tanudjojo, B;Shaikh, SS;Fenyi, A;Bousset, L;Agarwal, D;Marsh, J;Zois, C;Heman-Ackah, S;Fischer, R;Sims, D;Melki, R;Tofaris, GK; [2021]
Nature communications 12(1) 3817
-
A high-throughput screen for TMPRSS2 expression identifies FDA-approved compounds that can limit SARS-CoV-2 entry
Chen, Y;Lear, TB;Evankovich, JW;Larsen, MB;Lin, B;Alfaras, I;Kennerdell, JR;Salminen, L;Camarco, DP;Lockwood, KC;Tuncer, F;Liu, J;Myerburg, MM;McDyer, JF;Liu, Y;Finkel, T;Chen, BB; [2021]
Nature communications 12(1) 3907
-
Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance
Pietilä, EA;Gonzalez-Molina, J;Moyano-Galceran, L;Jamalzadeh, S;Zhang, K;Lehtinen, L;Turunen, SP;Martins, TA;Gultekin, O;Lamminen, T;Kaipio, K;Joneborg, U;Hynninen, J;Hietanen, S;Grénman, S;Lehtonen, R;Hautaniemi, S;Carpén, O;Carlson, JW;Lehti, K; [2021]
Nature communications 12(1) 3904
-
Residue 6.43 defines receptor function in class F GPCRs
Turku, A;Schihada, H;Kozielewicz, P;Bowin, CF;Schulte, G; [2021]
Nature communications 12(1) 3919
-
Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain
Shukla, S;Ying, W;Gray, F;Yao, Y;Simes, ML;Zhao, Q;Miao, H;Cho, HJ;González-Alonso, P;Winkler, A;Lund, G;Purohit, T;Kim, E;Zhang, X;Ray, JM;He, S;Nikolaidis, C;Ndoj, J;Wang, J;Jaremko, Ł;Jaremko, M;Ryan, RJH;Guzman, ML;Grembecka, J;Cierpicki, T; [2021]
Nature chemical biology 17(7) 784-793
-
Inhibition of aberrant tissue remodelling by mesenchymal stromal cells singly coated with soft gels presenting defined chemomechanical cues
Wong, SW;Tamatam, CR;Cho, IS;Toth, PT;Bargi, R;Belvitch, P;Lee, JC;Rehman, J;Reddy, SP;Shin, JW; [2021]
Nature biomedical engineering
-
STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma
Adane, B;Alexe, G;Seong, BKA;Lu, D;Hwang, EE;Hnisz, D;Lareau, CA;Ross, L;Lin, S;Dela Cruz, FS;Richardson, M;Weintraub, AS;Wang, S;Iniguez, AB;Dharia, NV;Conway, AS;Robichaud, AL;Tanenbaum, B;Krill-Burger, JM;Vazquez, F;Schenone, M;Berman, JN;Kung, AL;Carr [2021]
Cancer cell 39(6) 827-844.e10
-
Reduced neutralization of SARS-CoV-2 B.1.617 by vaccine and convalescent serum
Liu, C;Ginn, H;Dejnirattisai, W;Supasa, P;Wang, B;Tuekprakhon, A;Nutalai, R;Zhou, D;Mentzer, A;Zhao, Y;Duyvesteyn, H;López-Camacho, C;Slon-Campos, J;Walter, T;Skelly, D;Johnson, S;Ritter, T;Mason, C;Costa Clemens, S;Naveca, F;Nascimento, V;Nascimento, F;F [2021]
Cell