Signaling

No communication and cellular reactions without signaling molecules. Our microplate readers can characterize cytokine, hormone, and second messenger changes.

Cells not only receive extracellular cues, they also translate them into intracellular reactions. Extracellular signaling molecules comprise growth factors, hormones, ions, neurotransmitters, or cytokines.


Cellular reaction time covers from a few seconds to several hours. Accordingly, responses must either be triggered and measured instantly, or they need to be observed in living cells over a longer period of time. BMG LABTECH microplate readers provide injectors and a high sampling rate if fast reactions need to be captured. Further, the Atmospheric Control Unit regulates CO2 and O2 levels inside the reading chamber to provide a feel-good atmosphere for long-term cell experiments.


Signaling events rarely come alone, they take place simultaneously or in concert. In order to clearly characterize signaling events, BMG LABTECH devices offer the possibility of reading several assays in just one well.

Resources

Search our Resources section for information about specific applications, literature citations, videos, blog articles and many other publications. Many of the resources provided are associated with current and previous instrument models and versions.

    • 2021

      5004944[0]

      Long-term antagonism and allosteric regulation of mu opioid receptors by the novel ligand, methocinnamox

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    • 2021

      5004944[0]

      Long-term antagonism and allosteric regulation of mu opioid receptors by the novel ligand, methocinnamox

      Read article
    • Chemical characterization of extracts of leaves of Kadsua coccinea (Lem.) A.C. Sm. by UHPLC-Q-Exactive Orbitrap Mass spectrometry and assessment of their antioxidant and anti-inflammatory activities

      Shi, S;Li, K;Peng, J;Li, J;Luo, L;Liu, M;Chen, Y;Xiang, Z;Xiong, P;Liu, L;Cai, W;[2022]

      Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

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    • Modulatory effect of IL-1 inhibition following lipopolysaccharide-induced neuroinflammation in neonatal microglia and astrocytes

      Pierre, WC;Londono, I;Quiniou, C;Chemtob, S;Lodygensky, GA;[2022]

      International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience

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    • Human adipose and synovial mesenchymal stem cells improve osteoarthritis in rats by reducing chondrocyte reactive oxygen species and inhibiting inflammatory response

      Liu, X;Liu, Y;He, H;Xiang, W;He, C;[2022]

      Journal of clinical laboratory analysis

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