Aggregation of misfolded proteins leads to diseases like Parkinson’s, Alzheimer’s or prion disease. We have the dedicated reader for aggregation assays.
Methods that answer biochemical question are as varied as the chemical processes in living organisms. They cover simple protein quantification assays such as Bradford or Lowry assay to adjust protein extracts for further analysis, as well as enzyme activity assays helping to find inhibitory and accelerating conditions. These assays benefit from BMG LABTECH´s kinetic read options, an Enhanced Dynamic Range for high intensity variations in a measurement and a suite of enzyme kinetic analysis options.
An achievement of the past 20 years has been the multitude of protein interaction assays that can be carried out in 96 to 1536 well plates. They replace lengthy or radioactive procedures and facilitate the screening for potential active substances.
BMG LABTECH microplate readers measure all these assays. They not only provide highest sensitivity and throughput, if necessary, they further assist in developing your own assays and adapting existing methods to your specific target.
Search our Resources section for information about specific applications, literature citations, videos, blog articles and many other publications. Many of the resources provided are associated with current and previous instrument models and versions.
Development of an AlphaLISA protein-protein interaction assay to screen for re-purposed drugs as targeted disruptorsQuinlin Hanson , Kelli Wilson , Min Shen , Zina Itkin , Richard Eastman , Paul Shinn , Matthew Hall , , NCATS, NIH, 03/2021
High-throughput ELISA ready to analyse in 90-minutes: 384-well SimpleStep ELISA with the PHERAstar FSXJamie Campbell (1) , Oliver Carney (2) , , (1) Abcam, Cambridge, UK , (2) BMG LABTECH, Aylesbury, UK, 01/2021
Time Resolved Fluorescence (TRF) immunoassay in 384-well format using a matched antibody pair kit and the PHERAstar FSXJamie Campbell (1) , Oliver Carney (2) , , (1) Abcam, Cambridge, UK , (2) BMG LABTECH, Aylesbury, UK, 12/2020
Fast and accurate detection of Alzheimer’s Disease targets with SimpleStep ELISA kits and SPECTROstar NanoMallori Milligan (1) , Scott Detmer (1) , Carl Peters (2), (1) Abcam, Cambridge, UK , (2) BMG LABTECH, Cary, NC, 08/2020
Immuno-oncology biomarker measurement with high sensitivity and speed using SimpleStep ELISA kits and SPECTROstar NanoMallori Milligan (1) , Scott Detmer (1) , Carl Peters (2), (1) Abcam, Cambridge, UK , (2) BMG LABTECH, Cary, NC, 06/2020
Optimizing your ELISA Assays
Monoclonal antibody drugs – a history of success and a bright future!
Protein measurement: find a suitable method
The absorbance spectrum of hemoglobin
Washingtonia filifera seed extracts inhibit the islet amyloid polypeptide fibrils formations and α-amylase and α-glucosidase activityRead article
Journal of enzyme inhibition and medicinal chemistry
A glycoengineered antigen exploiting a conserved protein O-glycosylation pathway in the Burkholderia genus for detection of glanders infectionsRead article
Anti-biofilm multi drug-loaded 3D printed hearing aidsRead article
Materials Science and Engineering: C
Electrochemical screening of genoprotective and antioxidative effectiveness of Origanum vulgare L. and its functionality in the prevention of neurodegenerative disordersRead article
Mitigation potential of selenium nanoparticles and riboflavin against arsenic and elevated temperature stress in Pangasianodon hypophthalmusRead article