Nephelometry
Nephelometry is a light scattering method to detect particles in liquid samples. The principle is to measure forwarded scattered light when a laser beam passes through a sample and the light is deflected by the particles. Compared to turbidimetry, which measures the loss of light when it passes straight through a well, the forward and side scatter technology with an angle up to 80 degrees used in nephelometry outperforms simple turbidimetry measurements. Most common applications include automated drug solubility screening, microbial growth kinetics, flocculation, and the monitoring of polymerization and precipitation.
BMG LABTECH has published numerous application notes (AN) on using nephelometry detection mode with various BMG LABTECH microplate readers including:
- Nephelometric Monitoring Growth of Candida albicans Using BMG LABTECH's NEPHELOstar (AN 174)
- Measurement of Rheumatoid Factor by NEPHELOstar Microplate Reader (AN 133)
- A fully automated solubility screen in 384-well plate format using nephelometry (AN 117)
The following BMG LABTECH microplate readers can be configured to perform nephelometry measurements:
 |
BMG LABTECH GmbH, Allmendgruen 8, D-77799 Ortenberg/Germany
Phone: +49 781 96968-0, Fax +49 781 96968-67, Impressum / Disclaimer
Copyright ©1995-2012 All Rights Reserved.