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Microplate Reader Application Compatibility

microplate reader use comparisonBMG LABTECH´s extensive product portfolio consists of multidetection and dedicated microplate readers. The table below was created as an example of the overview of the features of our most popular multidetection microplate readers as well as our dedicated microplate readers. This allows a fast check for compatibility of application and microplate reader. More than 40 common assays and fluorophores are assigned to appropriate microplate readers which enables you to choose the best suited instrument for customary and special applications. For a comprehenisve and detailed comparison of all of BMG LABTECH's microplate readers, please click here.

   Detection Modes
  PHERAstar
FS		 PHERAstar
Plus		 POLARstar
Omega		 SPECTROstar
Omega		 FLUOstar
OPTIMA		 LUMIstar
OPTIMA		 NOVO
star		 SPECTROstar Nano NEPHELO
star

CLARIO
star

UV/Vis absorbance
+
+
+
+
+
+
+
+
UV/Vis absorbance spectrum
+
+
+
+
+
Fluorescence intensity
+
+
+
+
+
+
FRET 
+
+
+
+
+
+
Fluorescence polarization
+
+
+
+
  
+
Time-resolved fluorescence
+
+
+
+
+
  
+
Time-resolved-FRET
+
+
+
 
+
AlphaScreen®
+
+
+
 
+
Luminescence
+
+
+
+
+
+
  
+
BRET
+
+
+
+
+
 
+
Sequential dual emission detection
+
+
+
+
+
+
  
+
Simultaneous dual emission detection
+
+
+
+
  
Multichromatic
+
+
+
+
+
+
+
  
+
Nephelometry (scattered light)
+
   Technical features
 PHERAstar
FS		 PHERAstar
Plus		 POLARstar
Omega		 SPECTROstar
Omega		 FLUOstar
OPTIMA		 LUMIstar
OPTIMA		 NOVO
star		 SPECTROstar Nano NEPHELO
star		 CLARIO
star
Monochromators
                  
+
Injectors
+
+
+
+
+
+
+
+
Pipettor and plate-to-plate transfer
+
 
45°C incubation
+
+
+
+
+
+
+
+
+
+
60°C incubation 
+
+
+
+
 
+
65°C incubation 
    
+
+
          
+
Cuvette Port (on-board)
               +  
Cuvette measurements with LVis Plate (ABS)
    
+
+
       +  
+
Low Volumes down to 2µL with LVis plate (ABS)
    
+
+
       +  
+
Automatic control of O2 and CO2 (ACU)
+
+
+
Port for gas mixtures
(gas vent)
+
+
+
+
+
+
+
Spectral fluorescence scanning
                 
+
Spectral luminescence scanning
                 
+
Absorbance UV/Vis spectrometer
+
+
+
+
+
6 - 384 well
+
+
+
+
+
+
+
+
+
+
6 - 1536 well
+
+
+
+
+
  
+
6 - 3456 well
+
 
   Assays
Endpoint assays
+
+
+
+
+
+
+
+
+
+
Kinetic assays
+
+
+
+
+
+
+
+
+
+
Well scanning
+
+
+
+
+
+
+
+
Absorbance UV/Vis spectrometer
+
+
+
+
+
ELISA (absorbance)
+
+
+
+
+
+
+
+
ELISA (luminescence)
+
+
+
  
+
+
+
+
ELISA (fluorescence)
+
+
+
  
+
+
+
Immunoassays
+
+
+
+
+
+
+
+
   Protein determination
Bradford, BCA, Lowry
+
+
+
+
+
+
 +
+
Protein (A280)
+
+
+
+
+
+
+
+
Low Volume protein samples
+
+
+
+
Cuvette protein samples
    
+
+
      
+
NanoOrange, CBQCA, Quant-iT
+
+
+
+
+
+
   Nucleic Acid Assays
DNA/RNA/Oligos (A260)
+
+
+
+
+
+
+
+
260/280
+
+
+
+
+
+
+
+
Low Volume DNA samples (2 µl)
    
+
+
      
+
+
Cuvette DNA samples
   
+
+
      
+
RiboGreen, PicoGreen, Hoechst, OliGreen
+
+
+
+
+
+
SNP genotyping
+
+
+
+
+
+
   Reporter Genes
ALP, beta-galactosidase
+
+
+
+
+
+
+
Beta-lactamase
+
+
+
+
+
+
+
Luciferase
+
+
+
+
+
+
+
Dual luciferase
+
+
+
+
+
+
CFP, GFP, YFP
+
+
+
+
+
+
   Cell viability/proliferation/death
MTT, XTT, Crystal Violet, SRB
+
+
+
+
+
+
+
+
Fluorescent Live/ Dead kits, Alamar Blue
+
+
+
+
+
+
Calcein AM, CyQUANT
+
+
+
+
+
+
SYTOX Green, ethidium homodimer
+
+
+
+
+
+
Hypoxia measurements
  
+
+
+  
Ischemia/ Reperfusion
  
+
+
   Enzyme Assays
ATP (luciferase)
+
+
+
+
+
+
+
+
NADH (dehydrogenases)
+
+
+
+
+
+
+
+
Phosphatases/ Kinases activity
+
+
+
+
+
+
+
Protease activity
+
+
+
+
+
+
+
+
+
   HTS Assays
HTRF® (Cisbio)
+
+
+
+
AlphaScreen® (Perkin Elmer)
+
+
+
+
DELFIA®(Perkin Elmer)
+
+
+
+
+
+
LANCE® (Perkin Elmer)
+
+
+
+
LanthaScreen (Invitrogen)
+
+
+ 
+
PolarScreen (Invitrogen)
+
+
n.t.
n.t.
+
Transcreener ADP2 FP (BellBrook Labs)
+
+
+
+
Z'-Lyte (Invitrogen)
+
+
+
+
+
+
Ion Channel - VSP (Invitrogen)
+
+
+
+
+
Multiplexing (Promega)
+
+
+
+
+
+
+
P450 (Promega)
+
+
n.t.
n.t.
n.t.
n.t.
+
DLR (Promega)
+
+
+
+
HitHunter (DiscoveRx, luminescence)
+
+
+
+
+
+
+
HitHunter (DiscoveRx, FP)
+
+
+
+
+
MycoAlert (Cambrex)
+
+
+
+
+
+
+
PK Light (Cambrex)
+
+
+
+
+
+
ATP bioluminescence
+
+
+
+
+
+
+
CyDye fluors FRET protease
+
+
+
+
+
+
Intracellular calcium (Ca2+ assay)
+
+
+
+
+
Luminescent ABEL antioxidant test
+
+
+
+
+
+
+
   Other
Solubility screening (nephelometric)
+
  
ORAC (antioxidant capacity)
+
+
+
+
+
Microbial growth
+
+
+
+
+
+
+
+
+
Mammalian and stem cell assays with special O2 and CO2 conditions
+
+
  +  
Endotoxin endpoint colorimetric
+
+
+
+
+
+
 +
+

"+" = available. Not all of the features mentioned above are available in the basic units or in all detection modes. Optional accessories may be necessary to perform certain assays. Please contact your local distributor for details. "n.t." = not tested.

Please note that upgrades to the next higher model are available within the individual microplate reader series.

HTRF is a registered trademark of Cisbio International.
Transcreener is a patented technology of BellBrook Labs.
DLReady is a trademark of Promega Corp.
AlphaScreen, AlphaLisa, Surefire, DELFIA, and LANCE are registered trademarks of PerkinElmer, Inc.
LanthaScreen is a registered trademark of Invitrogen Corp.