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Microplate Reader Application Compatibility

microplate reader use comparisonBMG LABTECH´s extensive product portfolio consists of multidetection and dedicated microplate readers. The table below was created as an example of the overview of the features of our most popular multidetection microplate readers as well as our dedicated microplate readers. This allows a fast check for compatibility of application and microplate reader. More than 40 common assays and fluorophores are assigned to appropriate microplate readers which enables you to choose the best suited instrument for customary and special applications. For a comprehenisve and detailed comparison of all of BMG LABTECH's microplate readers, please click here.

   Detection Modes
  PHERAstar
FS		 PHERAstar
Plus		 POLARstar
Omega		 SPECTROstar
Omega		 FLUOstar
OPTIMA		 LUMIstar
OPTIMA		 NOVO
star		 RUBY
star		 NEPHELO
star
UV/Vis absorbance
+
+
+
+
+
+
UV/Vis absorbance spectrum
+
+
+
Fluorescence intensity
+
+
+
+
+
FRET 
+
+
+
+
+
Fluorescence polarization
+
+
+
+
Time-resolved fluorescence
+
+
+
+
+
+
Time-resolved-FRET
+
+
+
+
AlphaScreen®
+
+
+
Luminescence
+
+
+
+
+
+
BRET
+
+
+
+
+
Sequential dual emission detection
+
+
+
+
+
+
Simultaneous dual emission detection
+
+
+
+
+
Multichromatic
+
+
+
+
+
+
+
Nephelometry (scattered light)
+
   Technical features
  PHERAstar
FS		 PHERAstar
Plus		 POLARstar
Omega		 SPECTROstar
Omega		 FLUOstar
OPTIMA		 LUMIstar
OPTIMA		 NOVO
star		 RUBY
star		 NEPHELO
star
Injectors
+
+
+
+
+
+
+
Pipettor and plate-to-plate transfer
+
38°C incubation
+
+
+
+
+
+
+
+
45°C incubation
+
+
+
+
+
+
+
60°C incubation 
+
+
+
+
CO2 incubation (gas vent)
+
+
+
+
+
+
Absorbance UV/Vis spectrometer
+
+
+
6 - 384 well
+
+
+
+
+
+
+
+
+
6 - 1536 well
+
+
+
+
6 - 3456 well
+
   Assays
 
Endpoint assays
+
+
+
+
+
+
+
+
+
Kinetic assays
+
+
+
+
+
+
+
+
+
Well scanning
+
+
+
+
+
+
Absorbance UV/Vis spectrometer
+
+
+
ELISA (absorbance / luminescence)
+
+
+
+
+
+
+
Immunoassays
+
+
+
+
+
+
+
   Protein determination
 
Bradford, BCA, Lowry
+
+
+
+
+
+
Protein (A280)
+
+
+
+
+
+
NanoOrange, CBQCA, Quant-iT
+
+
+
+
+
+
   Nucleic Acid Assays
 
DNA/RNA/Oligos (A260)
+
+
+
+
+
+
260/280
+
+
+
+
+
+
RiboGreen, PicoGreen, Hoechst, OliGreen
+
+
+
+
+
SNP genotyping
+
+
+
+
+
   Reporter Genes
 
ALP, beta-galactosidase
+
+
+
+
+
+
Beta-lactamase
+
+
+
+
+
+
Luciferase
+
+
+
+
+
+
Dual luciferase
+
+
+
+
+
CFP, GFP, YFP
+
+
+
+
+
   Cell viability/proliferation/death
 
MTT, XTT, Crystal Violet, SRB
+
+
+
+
+
+
Fluorescent Live/Dead kits, Alamar Blue
+
+
+
+
+
Calcein AM, CyQUANT
+
+
+
+
+
SYTOX Green, ethidium homodimer
+
+
+
+
+
   Enzyme Assays
 
ATP (luciferase)
+
+
+
+
+
+
NADH (dehydrogenases)
+
+
+
+
+
+
Phosphatases/Kinases activity
+
+
+
+
+
+
Protease activity
+
+
+
+
+
+
   HTS Assays
 
HTRF® (Cisbio)
+
+
+
+
AlphaScreen® (Perkin Elmer)
+
+
+
DELFIA®(Perkin Elmer)
+
+
+
+
+
+
LANCE® (Perkin Elmer)
+
+
+
LanthaScreen (Invitrogen)
+
+
+ 
PolarScreen (Invitrogen)
+
+
n.t.
n.t.
Transcreener ADP2 FP (BellBrook Labs)
+
+
+
Z'-Lyte (Invitrogen)
+
+
+
+
+
Ion Channel - VSP (Invitrogen)
+
+
+
+
Multiplexing (Promega)
+
+
+
+
+
+
P450 (Promega)
+
+
n.t.
n.t.
n.t.
n.t.
DLR (Promega)
+
+
+
+
HitHunter (DiscoveRx, luminescence)
+
+
+
+
+
+
HitHunter (DiscoveRx, FP)
+
+
+
+
MycoAlert (Cambrex)
+
+
+
+
+
+
PK Light (Cambrex)
+
+
+
+
+
+
ATP bioluminescence
+
+
+
+
+
+
CyDye fluors FRET protease
+
+
+
+
+
Intracellular calcium (Ca2+ assay)
+
+
+
+
Luminescent ABEL antioxidant test
+
+
+
+
+
+
   Other
 
Solubility screening (nephelometric)
+
ORAC (antioxidant capacity)
+
+
+
+
Microbial growth
+
+
+
+
+
+
+
Endotoxin endpoint colorimetric
+
+
+
+
+
+

"+" = available. Not all of the features mentioned above are available in the basic units or in all detection modes.Optional accessories may be necessary to perform certain assays. Please contact your local distributor for details. "n.t." = not tested.

Please note that upgrades to the next higher model are available within the individual microplate reader series.

HTRF is a registered trademark of Cisbio International.
Transcreener is a patented technology of BellBrook Labs.
DLReady is a trademark of Promega Corp.
AlphaScreen, AlphaLisa, DELFIA, and LANCE are registered trademarks of PerkinElmer, Inc.
LanthaScreen is a registered trademark of Invitrogen Corp.

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