NEPHELOstar Plus

The NEPHELOstar Plus is a new laser-based nephelometer that measures light-scattering. It is perfect for measuring compound solubility and bacterial/fungal/cellular growth in a microplate.

Based on light-scattering principals, the NEPHELOstar Plus has a greater dynamic range than absorbance instruments that measure the same assays using turbidity. New accessories such as the ACU, which independently controls both CO2 and O2 inside of the reader, ensure optimal conditions for cell growth assays performed on the NEPHELOstar Plus.

 

 

New Features – The NEPHELOstar Plus uses a more stable photodiode detection system that has lower background noise and a more stable signal than previous systems. In addition, the overall measurement counts, relative nephelometric units (RNUs), have increased to 2,000,000 RNUs/second.  

New Software – The NEPHELOstar Plus incoroprates the Omega software package utilizing new ribbon style menus, incorporating many key features, shortcuts, and hints found in the Omega series of microplate readers.

New Accessory - The NEPHELOstar Plus can now be accompanied by BMG LABTECH’s unique Atmospheric Control Unit (ACU), which independently regulates both CO2 and O2 inside of the microplate reader chamber. When performing cell growth assays, the ACU will optimally regulate the atmosphere for any cell type. In addition, the ACU can be used to mimic biological conditions such as hypoxia to see the effect on cell growth.

Technical information:

• Laser-based microplate nephelometer
• Measures light-scattering to detect insoluble particles
• Reads 6- to 384-well plates
• Up to two onboard reagent injectors
• Incubation and shaking
• Optional ACU for the regulation of both CO2 and O2
• Stacker and robot compatible

Applications:

• Drug compound solubility screening
• Quantification of macromolecules
  • Pharmaceutical products, proteins, drug compounds,
    blood components, organic substrates, polymerization reactions
• Immunoprecipitation
  • Antibody-antigen interaction
• Bacterial and fungal growth
• Monitoring of microorganisms
• ADME studies

Stay tuned for more information about the NEPHELOstar Plus microplate nephelometer that measures light-scattering.