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High Throughput Screening
GPCR (G-Protein Coupled Receptors)
[206 - 2.680]
Cellular Dopamine and Intracellular Calcium Signaling Using the Next Generation HTS Microplate Reader
Mark Koeppel, Invitrogen, Madison Wisconsin, USA; EJ Dell, BMG LABTECH, NC, USA
BMG LABTECH 2010
Article
[194 - 8.150]
FRET-based screening for potential modulators of the Galphai1 protein/GoLoco interaction
Hutsell SQ, Kimple AJ, Siderovski DP
BMG LABTECH 2009
Article
[196 - 2.620]
Using Intrinsic Tryptophan Fluorescence to Measure Heterotrimeric G-Protein Activation
Muller RE, Siderovski DP, Kimple AJ, Dell EJ
BMG LABTECH 2009
Article
[193 - 3.190]
Functional Screening of recombinant CHO-M1 cells using the PHERAstar from BMG LABTECH
Bernd Laffert and Franka Ganske
BMG LABTECH
HTRF IPOne assay with fresh cells from a growing culture and Frozen Instant Cells measured at Cell Culture Service (CCS), Hamburg, Germany.
Article
[157 - 2.500]
Calcium Detection Upon GPCR Stimulation Using the NOVOstar and Screen Quest
Liao J, Dell E.J.
ABD Bioquest, Sunnyvale, CA, USA, BMG LABTECH Inc, Durham, NC, USA 2007
Article
[143 - 4.230]
Study of GPCR pharmacology using the DiscoveRx HitHunter
Rainard JM, Mireylees SE, Darlison MG
BMG LABTECH 2006
Article
[142 - 1.030]
HitHunterTM IP3 Assay for GCPR Screening using the PHERAstar
Kauffman L, De La Llera, Angersbach S, Orban M
BMG LABTECH 2006
Article
[134 - 4.200]
New HitHunter cAMP XS+ Assay for GPCR Screening Using the PHERAstar
Kauffman L, De La Llera S, Orban M
BMG LABTECH 2006
Article
[107 - 2.013]
Rapid functional screening at dopamine receptors by measuring intracellular calcium with the NOVOstar fluorescence reader
Hoefgen B, Kassack MU.
Application Note PDF
Kinases, Cytochrome P450 and Oxygenase
[202 - 4.340]
Promega's ADP-Glo(TM) Kinase Assay performed on BMG LABTECH's PHERAstar FS and POLARstar Omega
Ganske, F, Dell, EJ, Shultz S
BMG LABTECH 2009
Article
[203 - 2.650]
Enzyme Kinetic Measurements for a Combinatorial Library of Inhibitors of Pseudomonas Elastase
George Cathcart, Brendan Gilmore, Brian Walker.
BMG LABTECH 2009
Article
[201 - 2.660]
The Transcreener® ADP2 FI Assay performed on PHERAstar and Omega microplate readers
Franka Ganske, BMG LABTECH, Offenburg, Germany; EJ Dell, BMG LABTECH, NC, USA / Meera Kumar, BellBrook Labs, Madison, USA
BMG LABTECH 2009
Article
[185 - 6.250]
Enzyme kinetic measurements performed on BMG LABTECH´s FLUOstar OPTIMA
Franka Ganske
BMG LABTECH 2009
Esterase activity was determined using the p-nitrophenyl acetate (pNPA) assay. Km and Vmax were calculated using different calculation methods (e.g. Michaelis-Menten and Lineweaver-Burk).
Article
[183 - 1.180]
New Transcreener® ADP2 FP Assay performed on BMG LABTECH's POLARstar Omega
Larson B, Ganske F, Dell EJ
BMG LABTECH 2008
Article
[182 - 1.170]
New Transcreener® ADP2 FP Assay performed on BMG LABTECH's PHERAstar Plus HTS Microplate Reader
Larson B, Ganske F, Dell EJ
BMG LABTECH 2008
Article
[186 - 7.120]
AlphaScreen® Phosphotyrosine Assay Performed on a FLUOstar Omega and a POLARstar Omega
Franka Ganske
BMG LABTECH 2008
In this application note AlphaScreen® instrument settings and sensitivity as well as Z´value of a tyrosine kinase assay are presented. The measurements were done using Omega instruments.
Article
[179 - 2.580]
Fluorometric determination of extracellular enzyme activities in peat using the FLUOstar OPTIMA
Bonnett, S.A.F., Leah, R., and Maltby, E
BMG LABTECH 2008
Article
[167 - 6.180]
Comparison of Thioredoxin Activity in Cortical Neurons and Glial Cells using the FLUOstar OPTIMA
Papadia S, Léveillé F and Hardingham GE
BMG LABTECH 2008
The thioredoxin assay used in this application note is based on different redox reactions leading to the release of thionitrobenzoic acid. The resulting bright yellow absorbance signal is measured at 405 nm.
Article
[152 - 1.140]
Transcreener® ADP Fluorescence Polarization Assay Performed on the PHERAstar
Ganske F, Dell EJ, Larson B
BMG LABTECH 2008
Article
[126 - 7.100]
PHERAstar: A Next Generation Multimode Plate Reader for Sophisticated HTS Assays
Orban M, Angersbach S, Hoffman R, Buros M.
BMG LABTECH 2005
Herein we show the capability of the PHERAstar to measure challenging assays in HTS well format. Assays include Far Red PolarScreen® Kinase, cAMP AlphaScreen® and TNFa using the HTRF® technique.
Application Note PDF
[151 - 4.250]
Promega´s P450-Glo Luminescent Cytochrome P450 Assay Using the FLUOstar OPTIMA
Cali J, Dell EJ
Promega Corporation, BMG LABTECH, Germany
Article
[153 - 7.110]
Detection of tyrosine kinase activity using the PHERAstar in AlphaScreen® mode
Ganske F and Orban M.
BMG LABTECH, Germany, 2007
Laser-based AlphaScreen® is demonstrated in this application note. PHERAstar instrument settings are given and a titration curve of biotinylated and phosphorylated polypeptide (biot-LCK-P) is presented.
Article
[141 - 2.450]
ADP HunterTM Assay for HTS of Kinase Inhibitors using the PHERAstar
Kauffman L, Hguyen U, Angersbach S, Orban M
BMG LABTECH 2006
Article
[132 - 2.400]
Development of a post-reaction derivatisation and Fluorescence assay for 2-OG dependent dioxygenases
McNeill LA, Hewitson KS, Schonfeld CJ, Bethge L.
BMG LABTECH 2004
Article
[131 - 4.180]
Cambrex PKLight Protein Kinase Assay on the PHERAstar plate reader
Paine A, Walker L.
BMG LABTECH 2004
Article
[127 - 3.127]
A novel PI 3-Kinase assay utilising HTRF® technology on the RUBYstar
Rossant CJ, Brown JP, Marshall ML.
BMG LABTECH 2004
Article
Second Messenger Signalling; cAMP
[126 - 7.100]
PHERAstar: A Next Generation Multimode Plate Reader for Sophisticated HTS Assays
Orban M, Angersbach S, Hoffman R, Buros M.
BMG LABTECH 2005
Herein we show the capability of the PHERAstar to measure challenging assays in HTS well format. Assays include Far Red PolarScreen® Kinase, cAMP AlphaScreen® and TNFa using the HTRF® technique.
Application Note PDF
[134 - 4.200]
New HitHunter cAMP XS+ Assay for GPCR Screening Using the PHERAstar
Kauffman L, De La Llera S, Orban M
BMG LABTECH 2006
Article
Second messenger Signalling; Calcium
[206 - 2.680]
Cellular Dopamine and Intracellular Calcium Signaling Using the Next Generation HTS Microplate Reader
Mark Koeppel, Invitrogen, Madison Wisconsin, USA; EJ Dell, BMG LABTECH, NC, USA
BMG LABTECH 2010
Article
[157 - 2.500]
Calcium Detection Upon GPCR Stimulation Using the NOVOstar and Screen Quest
Liao J, Dell E.J.
ABD Bioquest, Sunnyvale, CA, USA, BMG LABTECH Inc, Durham, NC, USA 2007
Article
[104 - 2.025]
Intracellular Calcium Assay performed on NOVOstar Microplate Reader
Heding A.
BMG LABTECH
Article
[107 - 2.013]
Rapid functional screening at dopamine receptors by measuring intracellular calcium with the NOVOstar fluorescence reader
Hoefgen B, Kassack MU.
Application Note PDF
Second messenger Signalling; Inositol Phosphate
[142 - 1.030]
HitHunterTM IP3 Assay for GCPR Screening using the PHERAstar
Kauffman L, De La Llera, Angersbach S, Orban M
BMG LABTECH 2006
Article
[137 - 3.130]
HTRF® IP-One Assay Performed on the PHERAstar and RUBYstar Plate Readers
Orban M, Degorce F, Tardieu JL
BMG LABTECH 2005
Article
[127 - 3.127]
A novel PI 3-Kinase assay utilising HTRF® technology on the RUBYstar
Rossant CJ, Brown JP, Marshall ML.
BMG LABTECH 2004
Article
Ion Channels (Electrophysiology)
[175 - 2.560]
Measuring Mitochondrial Membrane Potential using the FLUOstar Omega Microplate Reader
Heather Mortiboys and Oliver Bandmann
BMG LABTECH 2008
Article
[173 - 1.150]
Performance of the PredictorTM hERG Fluorescence Polarization Assay Kit using the PHERAstar
Dell EJ
BMG LABTECH 2008
Article
[123 - 8.110]
Ion channel assay development using Invitrogen's FRET-based voltage sensor probes
Hoffman RL, Duff S, Qadir N.
Invitrogen Corporation, Madison, WI 53719, USA
Article
HTRF (Homogeneous Time-Resolved Fluorescence) Assays
[193 - 3.190]
Functional Screening of recombinant CHO-M1 cells using the PHERAstar from BMG LABTECH
Bernd Laffert and Franka Ganske
BMG LABTECH
HTRF IPOne assay with fresh cells from a growing culture and Frozen Instant Cells measured at Cell Culture Service (CCS), Hamburg, Germany.
Article
[177 - 3.170]
HTRF®IP-One Terbium-based assay performed on BMG LABTECH´s PHERAstar Plus
Ganske F, Jacquemart L, Jean A, Lebreton ML, Tardieu JL
BMG LABTECH 2008
Article
[126 - 7.100]
PHERAstar: A Next Generation Multimode Plate Reader for Sophisticated HTS Assays
Orban M, Angersbach S, Hoffman R, Buros M.
BMG LABTECH 2005
Herein we show the capability of the PHERAstar to measure challenging assays in HTS well format. Assays include Far Red PolarScreen® Kinase, cAMP AlphaScreen® and TNFa using the HTRF® technique.
Application Note PDF
[154 - 3.160]
Cisbio´s HTRF® cortisol assay performed on the PHERAstar
Ganske F, Tardieu JL and Degorce F.
BMG LABTECH, Germany and Cisbio International, France
Article
[137 - 3.130]
HTRF® IP-One Assay Performed on the PHERAstar and RUBYstar Plate Readers
Orban M, Degorce F, Tardieu JL
BMG LABTECH 2005
Article
Solubility Measured with Nephelometry
[174 - 5.120]
Nephelometric Monitoring Growth of Candida albicans Using BMG LABTECH's NEPHELOstar
U.-C. Hipler
BMG LABTECH 2008
Article
[117 - 5.101]
A fully automated solubility screen in 384-well plate format using nephelometry
Green C, McKee S, Saunders K.
BMG LABTECH 2003
Article
Single Nucleotide Polymorphisms (SNP Genotyping)
[187 - 2.640]
Application of the Amplifluor® SNPs Genotyping System using a FLUOstar OPTIMA microplate reader
Hamilton A, Liang R, Whittle B
BMG LABTECH 2010
Article
[160 - 8.130]
High Speed FRET based SNP Genotyping Measurement on the PHERAstar
Robinson P and Ganske F
BMG LABTECH 2007
Article
[129 - 8.120]
Use of the PHERAstar for SNP genotyping chemistry development and high throughput production genotyping
Robinson P.
BMG LABTECH 2004
Article
Reporter Gene Assays
[199 - 4.330]
Monitoring Bacterial Cell-to-Cell Communication "Quorum sensing" Using FLUOstar OPTIMA
Eboigbodin KE and Robinson GK
BMG LABTECH 2009
Article
[184 - 6.240]
Multiplex Analysis of Inflammatory Cytokines from Primary Human Macrophages using a FLUOstar Omega
Mutch BE, Willetts K, Timms E, Foxwell BMJ
BMG LABTECH 2008
The protein concentration of different inflammatory cytokines (e.g. TNFa or IL-6) were determined with the help of ELISA and Luciferase Reporter Gene Assay (DLR).
Article
[172 - 4.300]
Dual luciferase assay to assess the replication of the hepatitis C virus subgenomic replicon
Gretton S, Harris M
BMG LABTECH 2008
Article
[165 - 4.280]
Dual Luciferase Reporter (DLR) Assay Certification on the Omega Series of Readers
Dell EJ
BMG LABTECH 2007
Article
Protein-Protein/Protein-DNA interactions
[190 - 7.130]
Homogeneous IgG AlphaLISA® assay performed on BMG LABTECH's PHERAstar Plus
Franka Ganske and Keith Ansell
BMG LABTECH 2009
Quantitative determination of the most present immunoglobulin in plasma: IgG. Standard curves and PHERAstar Plus instrument settings for AlphaLISA® are presented.
Article
[180 - 1.160]
High-throughput protein-DNA affinity measurements using fluorescence anisotropy
Veprintsev DB
BMG LABTECH 2008
Article

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