Additional Assays
BRET (Bioluminescence resonance energy transfer) assays
[120 - 9.110] Simultaneous dual emission detection for fast kinetic BRET assays Orban M. BMG LABTECH 2003 BRET is an advanced cell-based assay technology for proteomics, including receptor research and the mapping of signal transduction pathways. Article [118 - 9.100] BRET assays performed on the FLUOstar OPTIMA Orban M. BMG LABTECH 2002 BRET is an advanced cell-based assay technology for proteomics, including receptor research and the mapping of signal transduction pathways. Application Note PDF
FRET (Fluorescence Resonance Energy Transfer) assays
[194 - 8.150] FRET-based screening for potential modulators of the Galphai1 protein/GoLoco interaction Hutsell SQ, Kimple AJ, Siderovski DP BMG LABTECH 2009 CFP-YFP FRET based assay utilized to screen for potential inhibitors Article [163 - 8.140] SUMO FRET-based assays performed on BMG LABTECH's NOVOstar Martin SF Screening and analyzing of small ubiquitin-like modifiers on the NOVOstar Article [122 - 8.100] Use of CyDye Fluors for Improved FRET Protease Assays on BMG POLARstar Fluorescence Microplate Reader George J, Norey C. GE Healthcare CyDye™ labeled peptides are used as substrates in protease assays Article Link
[204 - 2.670] Analysis of migration using the OrisTM Cell Migration Assay-TriCoated kit on the Polarstar Omega Iman van den Bout BMG LABTECH 2009 Real-time monitoring of cell migration on different ECM components Article [144 - 2.460] Analysis of Prostate Tumour Cell Invasion Using BD FluoroBlok and FLUOstar OPTIMA Hart CA , Clarke NW, Brown MD Paterson Institute for Cancer Research, University of Manchester, Manchester, UK Cell migration was followed in real-time analysis using the BD Fluoro-Blok" system Article
ADME (Absorption, Distribution, Metabolism and Elimination)
[151 - 4.250] Promega´s P450-Glo Luminescent Cytochrome P450 Assay Using the FLUOstar OPTIMA Cali J, Dell EJ Promega Corporation, BMG LABTECH, Germany Rapid and reliable detection of cytochrome P450 activity with the help of firefly luciferase Article
[154 - 3.160] Cisbio´s HTRF® cortisol assay performed on the PHERAstar Ganske F, Tardieu JL and Degorce F. BMG LABTECH, Germany and Cisbio International, France Activity of key metabolic enzyme measured and EC50 values for cortisol and IC50 values for common inhibitors determined Article
[178 - 6.230] Reaction optimization by parallel kinetic studies with the FLUOstar Omega Redman JE BMG LABTECH 2008 Relative reaction rates of the metallation of tetraphenylporphyrin (TTP) with zinc were measured. The values for twelve different solvents were determined in parallel. Article [145 - 6.140] Plasso EpranEx™ ready to use heparin-binding plate with the FLUOstar OPTIMA plate reader Wiles M. Plasso Technology Ltd., Sheffield, UK A detection system to identify and characterise heparin binding proteins is introduced. Article [147 - 4.240] LUMIstar in the production and quality control for ROTAS on-site test reagents Dix A Cybersense Biosystems Ltd, Oxon, UK BMG LABTECH microplate reader used in the quality control of reagent manufacturing Article [136 - 4.210] LUX Biotechnology GLOWELL luminometry standards on the POLARstar OPTIMA Perfect E, Hickey P. BMG LABTECH 2004 Measurement of certified calibration reference materials in comparison to biological controls Article
[208 - 2.690] A Fast and Simple Method For Measuring P-Glycoprotein (Pgp) Inhibition Melchior DL, Sharom FJ, Dell EJ BMG LABTECH 2010 The Fluorosome®-trans-pgp fluorescence intensity assay specifically measures the inhibition of Pgp multidrug transporter Article [205 - 1.190] Membrane Fluidity Measurements Using UV Fluorescence Polarization and the POLARstar Omega Kushnareva Y, Dell EJ BMG LABTECH 2009 DHP used as membrane-bound fluorophore in both liposomes and mitochondrial membranes Article
[215 - 6.310] Miniaturised Platelet Aggregation Assays using the NOVOstar Microplate Reader Vaiyapuri S and Gibbins JM BMG LABTECH 2011 Platelet aggregation induced by addition of agonist measured on the NOVOstar in absorbance mode. Article [212 - 2.710] Promotion of Aggregation as a Means of Assessing the Stability of Antibody Molecules Alison Turner UCB BMG LABTECH 2011 Thioflavin T aggregation assay to determine antibody stability Article
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